PMID: 6969599Jul 15, 1980Paper

Evaluation of some nonspecific immunological parameters in patients with oral cavity carcinoma undergoing cryosurgery

Bollettino della Società italiana di biologia sperimentale
M AiroldiM Fazio

Abstract

The authors have evaluated general immunocompetence of 10 pts. after a cryosurgery treatment for oral squamous cell carcinoma. Serum immunoglobulin levels, C3 - C4, peripheral lymphocytes, E-rosette forming cells, lymphocyte response to PHA were analized before and after 7 and 14 days a single cryotreatment. Humoral immunity was scarcely modified by the cryosurgery; on the contrary a statistically significant augment of peripheral large lymphocytes (p < 0,0001), T-lymphocytes (p < 0,025) and lymphocyte response to PHA (p < 0,001) was found both after 7 and 14 days.

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