PMID: 16524095Mar 10, 2006Paper

Evaluation of split/splitless operation and rapid heating of a multi-bed sorption trap used for gas chromatography analysis of large-volume air samples

Journal of Separation Science
Joshua J Whiting, R D Sacks

Abstract

The effects of split-flow operation and rapid trap heating on injection-plug widths from an electrically heated, microscale, multibed sorption trap were evaluated. The sorption trap has been designed to quantitatively collect volatile organic compounds from large-volume vapor samples and inject them into a gas chromatograph. Previous trap designs resulted in injection-plug widths of typically a second or more, and this significantly degraded chromatographic resolution, particularly for early-eluting sample components and for high-speed separations. Injection-plug widths are determined by the heating rate of the trap during sample desorption and the volumetric flow rate of carrier gas through the trap. The effects of the heating rate of the trap and carrier gas velocity through the trap on the injection-plug widths of pentane, octane, and undecane were studied. Carrier gas velocity through the trap was increased by splitting the flow coming from the trap between the column and a vent. This decreases transport time from the trap to the column, and thus decreases injection-plug widths. The heating rate for the trap was increased by increasing the applied voltage in the range from 4 to 30 V. Increasing the heating rate decreases th...Continue Reading

References

Jul 31, 2001·Analytical Chemistry·C J Lu, E T Zellers
Aug 16, 2003·Analytical Chemistry·Juan M Sanchez, Richard D Sacks
Sep 22, 2005·Lab on a Chip·Chia-Jung LuEdward T Zellers
May 1, 1996·Analytical Chemistry·A CalogirouD Kotzias
Jun 1, 1999·Analytical Chemistry·C LeonardR Sacks

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.