Evaluation of subcutaneous ICD early performance in hypertrophic cardiomyopathy from the pooled EFFORTLESS and IDE cohorts

Heart Rhythm : the Official Journal of the Heart Rhythm Society
Pier LambiaseBradley P Knight

Abstract

The subcutaneous implantable cardioverter-defibrillator (S-ICD) is a potential alternative to transvenous systems in hypertrophic cardiomyopathy (HCM) where lead complications are a significant issue. To compare the S-ICD efficacy of defibrillation threshold (DFT) testing, arrhythmia therapy, and complications in HCM versus non-HCM patients. Outcomes of patients with HCM implanted with S-ICD were compared to non-HCM S-ICD recipients using pooled data from a total of 872 subjects enrolled in the EFFORTLESS Registry and US IDE study. The cohort included 99 HCM (75% male) and 773 non-HCM (72% male) patients with a median follow-up of 637 days. The HCM cohort was younger and more likely to receive a primary-prevention S-ICD (88.5% vs 67.5%, P < .0001). During implant testing, successful defibrillation at ≤80 J was achieved in 98.9% of HCM and 98.5% of non-HCM patients. One year postoperative complication-free rates were similar: 92.7% in HCM (with no lead complications) versus 89.5% in non-HCM. There were 3 appropriate shocks for ventricular tachycardia in 3 HCM patients that were all converted by the first shock. Overall final shock conversion efficacy was 100% in HCM versus 98% in non-HCM (P = ns). Inappropriate shocks occurred i...Continue Reading

References

Apr 30, 1998·Journal of the American College of Cardiology·J PrimoP Brugada
Mar 11, 2003·Journal of Cardiovascular Electrophysiology·Uwe DorwarthEllen Hoffmann
Apr 28, 2004·The American Journal of Cardiology·Irandi JayatillekeChristopher Semsarian
Jul 27, 2007·JAMA : the Journal of the American Medical Association·Barry J MaronPaolo Bruzzi
Nov 26, 2010·Journal of Cardiovascular Electrophysiology·Ernest M QuinMichael R Gold
Nov 19, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Constantinos O'MahonyPerry Elliott
Mar 1, 2012·Pacing and Clinical Electrophysiology : PACE·Susanne S PedersenDominic A M J Theuns
Dec 11, 2013·Journal of Cardiovascular Electrophysiology·Louise R A Olde NordkampReinoud E Knops
Dec 11, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kirsten M KooimanJoris R de Groot
Mar 29, 2014·European Heart Journal·Pier D LambiaseUNKNOWN EFFORTLESS Investigators
Jan 13, 2015·Journal of Cardiovascular Electrophysiology·Amy J BrisbenMichael R Gold
May 23, 2015·Journal of Cardiovascular Electrophysiology·Pietro FranciaCamillo Autore
Sep 13, 2015·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Niccolo' MauriziFranco Cecchi

❮ Previous
Next ❯

Citations

Nov 20, 2016·Journal of Cardiovascular Electrophysiology·Pietro FranciaCamillo Autore
Dec 13, 2016·Pacing and Clinical Electrophysiology : PACE·Michael R GoldLucas Boersma
Mar 25, 2018·Pacing and Clinical Electrophysiology : PACE·Robert LarbigJulia Köbe
Jun 7, 2018·Journal of Cardiovascular Electrophysiology·Markus BettinGerrit Frommeyer
Sep 18, 2018·Journal of Cardiovascular Medicine·Federico MiglioreDomenico Corrado
May 31, 2018·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Serkan CaySerkan Topaloglu
Dec 24, 2018·Journal of Cardiovascular Electrophysiology·Ankur A KarnikKevin M Monahan
Feb 13, 2018·Herzschrittmachertherapie & Elektrophysiologie·Robert LarbigJulia Köbe
Oct 6, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Kevin WillyGerrit Frommeyer
Nov 2, 2019·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Kevin WillyGerrit Frommeyer
May 10, 2020·Pacing and Clinical Electrophysiology : PACE·Idris HardingPaul A Scott
Jun 17, 2020·Expert Review of Cardiovascular Therapy·Muhammad R AfzalRaul Weiss
Mar 15, 2018·Journal of Clinical Medicine·Carmen AdduciPietro Francia
Mar 20, 2019·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Nils BögeholzLars Eckardt
Jun 11, 2020·High Blood Pressure & Cardiovascular Prevention : the Official Journal of the Italian Society of Hypertension·Carmen AdduciPietro Francia
Jan 11, 2020·European Journal of Heart Failure·C Vaughan TuohyStephen B Heitner
Sep 14, 2019·Circulation Research·Barry J MaronMartin S Maron
Nov 7, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Claude DaubertCecilia Linde
Sep 9, 2020·Circulation. Arrhythmia and Electrophysiology·Ethan J RowinBarry J Maron
Nov 21, 2020·JACC. Clinical Electrophysiology·Martin C BurkeMichael R Gold
Jan 29, 2021·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Barry J MaronMartin S Maron
Feb 18, 2021·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Diego Jiménez-SánchezIgnacio Fernández-Lozano
Feb 19, 2021·Circulation Research·Natalia A TrayanovaJulie K Shade
Mar 13, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Joseph CodyMichael Essandoh
Apr 21, 2021·Pacing and Clinical Electrophysiology : PACE·Sugeevan SavarimuthuAmer Harky
Jun 7, 2021·Journal of Electrocardiology·Jan WagnerJulia Köbe
Jul 22, 2021·Heart Failure Reviews·Thomas GossiosGeorgios K Efthimiadis
Dec 31, 2021·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Pietro FranciaCamillo Autore

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Related Papers

Heart Rhythm : the Official Journal of the Heart Rhythm Society
Jason M GarnreiterElizabeth V Saarel
International Journal of Cardiology
Louise Olde NordkampReinoud Knops
Clinical Research in Cardiology : Official Journal of the German Cardiac Society
Gerrit FrommeyerFlorian Reinke
Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Reinoud KnopsIDE and EFFORTLESS investigators
© 2022 Meta ULC. All rights reserved