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Evaluation of Super-Boosted Lopinavir/Ritonavir in combination with Rifampin in HIV-1-infected Patients with Tuberculosis

International Journal of Antimicrobial Agents

Nov 11, 2019

Catherine BoulangerCharles Peloquin

Abstract

Rifampin induces the metabolism of many medications. To overcome the reduction in serum concentrations of lopinavir/ritonavir (LPV/r) when used with rifampin, 800/200 mg or 400/400 mg doses are used. To evaluate the super-boosted LPV/r (400/400mg) combination in HIV-TB patients for adeq...read more

Mentioned in this Paper

Treatment Protocols
Tuberculosis
Lopinavir
HIV Infections
Adverse Effects
Evaluation
Pharmaceutical Preparations
Serum
Patient Visit
Metabolism
2
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Evaluation of Super-Boosted Lopinavir/Ritonavir in combination with Rifampin in HIV-1-infected Patients with Tuberculosis

International Journal of Antimicrobial Agents

Nov 11, 2019

Catherine BoulangerCharles Peloquin

PMID: 31704214

DOI: 10.1016/j.ijantimicag.2019.10.021

Abstract

Rifampin induces the metabolism of many medications. To overcome the reduction in serum concentrations of lopinavir/ritonavir (LPV/r) when used with rifampin, 800/200 mg or 400/400 mg doses are used. To evaluate the super-boosted LPV/r (400/400mg) combination in HIV-TB patients for adeq...read more

Mentioned in this Paper

Treatment Protocols
Tuberculosis
Lopinavir
HIV Infections
Adverse Effects
Evaluation
Pharmaceutical Preparations
Serum
Patient Visit
Metabolism
2

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