Evaluation of survival of patients with locally advanced head and neck cancer treated in a single center.

Brazilian Journal of Otorhinolaryngology
Fred Muller Dos SantosJuliana Fernandes Pavoni

Abstract

Even with improved treatment outcomes with multimodality approaches, the question of what is the best initial treatment for locally advanced head and neck cancer still remains unanswered. To review the overall survival of a large cohort of head and neck cancer, patients with locally advanced head and neck cancer treated in a single institution. We studied a cohort of patients with locally advanced head and neck cancer treated in our institution in the last fifteen years. To gather a large sample of patients with adequate follow-up time, a cross-check between ours and Fundação Oncocentro de São Paulo databases were done. We included patients with head and neck cancer, clinical or pathological staging III or IV, treated with surgery followed by radiotherapy or surgery plus chemoradiation or radiotherapy alone or chemoradiation alone. 796 patients with locally advanced head and neck cancer were included, 88% male, 44% age >60 years and 76% stage IV. The tumor location was the oral cavity (34%), oropharynx (27%), hypopharynx (17%) and larynx (17%). The treatment groups were chemoradiation alone (39.7%), surgery plus chemoradiation (26.3%), surgery followed by radiotherapy (18.5%) and radiotherapy alone (15.5%). Comparing the clinic...Continue Reading

References

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Citations

Jul 14, 2021·Journal of Digital Imaging·Vanessa De Araujo FariaLuiz Otavio Murta Junior
Jul 20, 2021·Nutrition and Cancer·Adriana SantosWilza Arantes Ferreira Peres

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