PMID: 15348095Sep 7, 2004Paper

Evaluation of the acute scarring response to the implant of different types of biomaterial in the abdominal wall

Journal of Materials Science. Materials in Medicine
J M BellónJ Buján

Abstract

Since the short-term, acute scarring process induced by a biomaterial may condition the evolution of the repair process, the present investigation evaluates the behavior of polytetrafluoroethylene (PTFE) and polypropylene (PL) biomaterials in the initial stages of repair. Three PTFE biomaterials (Mycro Mesh, Dual Mesh and Soft Tissue Patch) and one PL biomaterial (Marlex) were employed to repair defects created in the abdominal wall of New Zealand rabbits. Animals were sacrificed at 3 or 7 days. Specimens were obtained for light and scanning electron microscopy, and immunohistochemical analysis using the RAM-11 monoclonal antibody for rabbit macrophages. The PL implants showed substantial adhesion formation with viscera. Lower adhesion formation was detected in the PTFE implants. The evolution of the acute phase of the repair process was similar for each PTFE biomaterial. At 3 days post implant, an incipient neoperitoneum was detected which was fully established after 7 days. The behavior of the PL implant was similar, although a greater amount of reticular granulation was detected. The neoformed peritoneum was irregular. Few RAM-11-labeled macrophages were detected in all cases. The acute phase of the tissue repair process ind...Continue Reading

Citations

Jan 10, 2014·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Thomas G BarnesAyman S Abdelrazeq
Mar 17, 2016·Journal of Plastic Surgery and Hand Surgery·Victor M Hernández MartinezSara Pascoe Gonzalez
Apr 29, 2011·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Marta RodríguezJuan M Bellón
Mar 13, 2012·Expert Review of Medical Devices·David L Sanders, Andrew N Kingsnorth
May 9, 2007·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Juan M BellónJulia Buján
Jun 16, 2001·Journal of Biomedical Materials Research·F P DupuyG Renard
Jan 13, 2011·Seminars in Immunopathology·Marcel BinneböselKarsten Junge
Mar 13, 2019·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Sambit SahooKathleen A Derwin

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