Evaluation of the anatomic and hemodynamic abnormalities in tricuspid atresia before and after surgery using computational fluid dynamics

Medicine
Li-Jun ChenAi-Min Sun

Abstract

Analysis of hemodynamics inside tricuspid atresia (TA) chamber is essential to the understanding of TA for optimal treatment. In this study, we introduced a combined computational fluid dynamics (CFD) to simulate blood flow in the left ventricle (LV) to study the diastolic flow changes in TA.Real-time 3-dimentional echocardiography loops (ECHO) were acquired in normal control group, in TA patients before surgery (pre-op group) and after surgery (post-op group). ECHO loops were reconstructed and simulated by CFD, the geometric, volumetric changes, and vortices in the LV were studies and compare among 3 groups.Compared with the control group, pre-op TA patients demonstrated significant LV remodeling, manifesting with smaller LV length, larger diameter, width and spherical index, as well as lager volumes; post-op TA group showed revisions in values of both geometric and volumetric measurements. CDF also demonstrated the abnormality of vortices in the pre-op TA patients and the alteration of existence and measurements of vortex in postoperation group.Echo-based CFD modeling can show the abnormality of TA in both LV geometric, volumetric measurements and intracardiac vortices; and CFD is capable to demonstrate the alterations of LV ...Continue Reading

References

Sep 26, 1997·The Journal of Thoracic and Cardiovascular Surgery·T L GentlesG Wernovsky
Apr 28, 2000·Nature·P J KilnerM H Yacoub
Oct 4, 2005·Physical Review Letters·Gianni Pedrizzetti, Federico Domenichini
Nov 14, 2006·Journal of Biomechanics·F DomenichiniG Pedrizzetti
Feb 14, 2007·Circulation·Paul KhairyLise-Andrée Mercier
Mar 10, 2009·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Sherif F NaguehArturo Evangelisa
Oct 20, 2009·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Arash KheradvarDavid Sahn
Jan 15, 2011·JACC. Cardiovascular Imaging·Marvin A KonstamJames E Udelson
Jul 10, 2012·European Journal of Mechanics. B, Fluids·Trung Bao Le, Fotis Sotiropoulos
Oct 24, 2012·Journal of Magnetic Resonance Imaging : JMRI·Michael MarklOliver Wieben
Nov 24, 2012·Journal of Biomechanics·Ethan KungUNKNOWN Modeling Of Congenital Hearts Alliance (MOCHA)+ Investigators
May 15, 2013·Journal of Biomechanics·Jan O MangualGianni Pedrizzetti
Jan 9, 2015·Biomechanics and Modeling in Mechanobiology·Kevin D Lau, C Alberto Figueroa

❮ Previous
Next ❯

Citations

Jun 3, 2020·Journal of Cardiac Surgery·Anoop S SumalAhmed M H A M Mostafa

❮ Previous
Next ❯

Software Mentioned

Statistical Package for Social Sciences ( SPSS
Mimics
Tomtec View
Materialise
ICEM
- FLUENT
ANSYS

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.