PMID: 28530081May 23, 2017Paper

EVALUATION OF THE ASSOCIATION BETWEEN ANTIHYPERTENSIVE TREATMENT AND DEVELOPMENT OF STROKE

Harefuah
Margarita FraimovitchReuven Zimlichman

Abstract

An ischemic stroke is an event that occurs due to cerebral vascular disease and is directly related to the degree of vascular damage. This process is associated with atherosclerosis progression and is influenced by the presence of cardiovascular risk factors. One of the goals of our research was to examine whether specific medications used for treating hypertension are associated with the development of strokes. In a retrospective study of patients who were hospitalized between the years 2003-2008 due to a cerebrovascular accident (CVA) or a transient ischemic attack (TIA), 916 cases of stroke patients were reviewed. The patients were examined for the presence of background diseases including cardiovascular risk factors (hypertension, diabetes, dyslipidemia, renal failure, coronary artery disease). In the study, the most common stroke type was ischemic stroke (70.2%), one quarter of the patients (24.6%) suffered from TIA, and the smallest number of patients had hemorrhagic stroke (5.2%). The study demonstrated a discrepancy between the blood pressure level that was measured in the ER and the type of stroke. Also no correlation was observed between the blood pressure level measured in the ER, and the appearance of a recurring st...Continue Reading

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Cardiovascular Disorder in Diabetes

Diabetes is associated with an increased risk of cardiovascular disorders and heart failure. Discover the latest research here.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.