Evaluation of the Bayer microalbumin/creatinine urinalysis dipstick

Clinica Chimica Acta; International Journal of Clinical Chemistry
Helena M WildeMartha E Lyon

Abstract

The objective of this study was to evaluate the utility of the Bayer microalbumin/creatinine urine reagent strip compared to established laboratory methods. Random urine specimens from low and high risk pregnancy clinics as well as a random cohort from the community were analyzed for microalbumin and creatinine using both the reagent strip and the Roche Integra 700, according to manufacturers' specifications. Sensitivity and specificity were then calculated. For the pregnant cohorts the sensitivities ranged from 19% to 59%, and the range of specificities was 45.4% to 84.2%. Using the microalbumin/creatinine data from the community, the sensitivity and specificity of the strip were 52.4% and 97.6%, respectively. The poor sensitivity of the microalbumin/creatinine urine reagent strip to detect significant microalbuminuria will likely limit its usefulness as a screening tool.

References

Nov 1, 1995·The Australian & New Zealand Journal of Obstetrics & Gynaecology·M A Brown, M L Buddle
Sep 28, 2001·Journal of Clinical Laboratory Analysis·J F WallaceJ M Bucksa
Jun 28, 2003·Cleveland Clinic Journal of Medicine·Garabed Eknoyan
Mar 31, 2004·Obstetrics and Gynecology·Jason J S WaughMark D Kilby
Sep 17, 2004·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Lorna K PhelanGeorge Mangos
Mar 22, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·Jason J S WaughAidan W F Halligan
Jan 21, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·John H ContoisMichael J Thompson
Apr 25, 2007·Journal of Perinatology : Official Journal of the California Perinatal Association·D E E RizkE N Obineche

❮ Previous
Next ❯

Citations

Mar 4, 2011·Biosensors & Bioelectronics·R IrawanV Thaveeprungsriporn
Mar 1, 2014·Journal of Clinical Laboratory Analysis·Min-Chul ChoWon-Ki Min
Jul 19, 2017·The Pediatric Infectious Disease Journal·Torsak BunupuradahUNKNOWN HIV-NAT 015 Study Team
Apr 25, 2020·Journal of Nephrology·Guillaume RésimontPierre Delanaye
Dec 21, 2010·Analytica Chimica Acta·D RyanMegan Kendall

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.