Evaluation of the bispectral index as an indicator of degree of central nervous system depression in isoflurane-anesthetized horses

American Journal of Veterinary Research
Henning Andreas Haga, Nils I Dolvik

Abstract

To determine whether the bispectral index (BIS) can be used as an indicator of degree of CNS depression in isoflurane-anesthetized horses. 10 Standardbred and 6 Norwegian cold-blooded trotter stallions admitted for routine castration. A 2-channel referential electrode configuration was used to record EEG for calculation of BIS by the EEG monitor. The BIS was calculated before (awake) and after (sedated) administration of detomidine (0.01 mg/kg of body weight, IV) and butorphanol (0.01 mg/kg, IV). Anesthesia was induced with ketamine hydrochloride (2.5 mg/kg, IV) and diazepam (0.04 mg/kg, IV) and maintained with isoflurane delivered in oxygen. The BIS was calculated after 30 minutes of equilibration at an end-tidal isoflurane concentration of 1.4% (n = 8) or 1.9% (8) and recorded continuously during surgery. Bispectral index was significantly less in sedated and anesthetized horses, compared with awake horses. However, BIS was not significantly different between sedated and anesthetized horses. Mean BIS in horses anesthetized at 1.9% isoflurane was significantly greater, compared with horses anesthetized at an end-tidal concentration of 1.4%. Four horses in the 1.4% group moved during surgery, and BIS increased immediately prior...Continue Reading

References

Nov 1, 1994·Journal of Clinical Monitoring·J C Sigl, N G Chamoun
Mar 7, 2000·Anesthesia and Analgesia·J E HallT J Ebert
Apr 26, 2000·Anesthesiology·J BruhnS L Shafer
Sep 6, 2000·Journal of Cardiothoracic and Vascular Anesthesia·P RoffeyD Thangathurai
Oct 12, 2000·Journal of the American Academy of Child and Adolescent Psychiatry·Y Kaminer

❮ Previous
Next ❯

Citations

Apr 12, 2012·Journal of Veterinary Internal Medicine·D C WilliamsT A Holliday
Dec 16, 2003·American Journal of Veterinary Research·Philip A March, William W Muir
Jul 15, 2003·American Journal of Veterinary Research·María F Martín-CanchoJesús Usón-Gargallo
Jan 15, 2004·American Journal of Veterinary Research·Leigh A LamontWilliam J Tranquilli
Aug 23, 2005·American Journal of Veterinary Research·Joanna C MurrellLudo J Hellebrekers
Dec 2, 2015·Veterinary Anaesthesia and Analgesia·Rocio NavarreteJuan Morgaz
Jun 13, 2006·Veterinary Anaesthesia and Analgesia·Peter J A Bollen, Henrik Saxtorph
Sep 9, 2006·Journal of Veterinary Pharmacology and Therapeutics·J C Murrell, C B Johnson
Aug 13, 2011·Veterinary Anaesthesia and Analgesia·Ewaldo de Mattos-JuniorSilvia R G Cortopassi
Jul 11, 2012·Journal of Veterinary Pharmacology and Therapeutics·A de VriesJ W Sear
Dec 19, 2009·Veterinary Anaesthesia and Analgesia·Eliseo BeldaR Eddie Clutton
Mar 7, 2006·Research in Veterinary Science·María F Martín-CanchoJesús Usón-Gargallo
Sep 13, 2015·Veterinary Anaesthesia and Analgesia·Mauricio DeschkPaulo S P Santos
Dec 5, 2009·The Journal of Veterinary Medical Science·Kazuto YAMASHITAWilliam W MUIR
Sep 2, 2005·Veterinary Anaesthesia and Analgesia·Philip A March, William W Muir
Jan 30, 2015·Acta Cirúrgica Brasileira·Marcelo Augusto de AraújoPaulo Sergio Patto dos Santos
Apr 21, 2012·Laboratory Animals·Aura Silva, Luis Antunes
Apr 23, 2003·Anesthesia and Analgesia·Ken B JohnsonScott W McJames
Aug 26, 2006·Anesthesia and Analgesia·Red S HowardSam H Ridgway
Jan 22, 2020·Equine Veterinary Journal·Rocío Navarrete-CalvoMaría M Granados
Feb 3, 2020·Veterinary Anaesthesia and Analgesia·Patricia Ruíz-LópezMaría Del Mar Granados
Aug 13, 2011·Veterinary Anaesthesia and Analgesia·Flavia RestituttiOuti M Vainio
Oct 13, 2011·Veterinary Anaesthesia and Analgesia·Elise H BleijenbergLudo J Hellebrekers

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.