PMID: 6161261Jan 23, 1981Paper

Evaluation of the buffy-coat smear for rapid detection of bacteremia

JAMA : the Journal of the American Medical Association
H Reik, S J Rubin

Abstract

Buffy-coat smears prepared from 599 blood samples, obtained simultaneously with blood for culture, were examined for bacteria. Each blood sample was quantitatively cultured on chocolate agar. Twenty-one blood cultures (3.6%) from 17 patients were positive. Two (11.7%) of the 17 patients had positive buffy-coat smears. One patient had two positive smears, for a total of three positive buffy-coat smears from 21 positive blood cultures. Chart reviews were performed for two patients with positive buffy-coat smears, three patients with positive blood cultures (containing the same organisms as the two study patients) but negative buffy-coat smears, and six additional patients who had had positive buffy-coat smears between 1974 and 1979. Of the eight patients with positive smears, six (75%) were infected with Gram-positive cocci, three of which were Streptococcus pneumoniae. Mortality was 100%.

Citations

Aug 1, 1986·Journal of Clinical Pathology·D CumminsM Watts
Mar 1, 1996·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·S J Wagner
Feb 1, 1983·The Journal of Pediatrics·E R WaldF P Wucher
Aug 1, 1986·Journal of Clinical Pathology·M F Al-ZahawiT L Shrestha
Aug 1, 1982·European Journal of Clinical Microbiology·D G BeckwithD C Etowski
Jan 1, 1987·Scandinavian Journal of Infectious Diseases·P A RistucciaB A Cunha

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