Evaluation of the clinical efficacy of a mouthwash and oral gel containing the antimicrobial proteins lactoperoxidase, lysozyme and lactoferrin in elderly patients with dry mouth--a pilot study

Gerodontology
Jose Antonio Gil-MontoyaMiguel Angel González-Moles

Abstract

To evaluate the clinical efficacy of a mouthwash and oral gel containing the antimicrobial proteins lactoperoxidase, lactoferrin and lysozyme, in a sample of elderly individuals with dry mouth. Twenty elderly institutionalised subjects with dry mouth and with a certain degree of independence for daily life activities were included in this pilot study. A randomised, double blind and cross-over design was used. The study variables comprised subjective dry mouth sensation, the severity of discomfort assessed by means of a visual analogical scale (VAS), the Oral Health Impact Profile (OHIP), the presence of signs and symptoms of dry mouth, sialometry and Candida albicans culture. All the variables were recorded before and after each of the two periods of the study. The 20 selected subjects we made up of 16 women and four men, with a mean age of 81.3 years. Improvement was observed on analysing the data between the first and second intervention period in terms of the OHIP values, the presence of dry mouth, and the need to drink fluids to swallow. However, the improvement in certain variables before and after treatment did not take a positive course in all cases, and some subjects even improved with placebo. The evaluated mouthwash a...Continue Reading

References

Dec 15, 1990·Lancet·J A Ship, B J Baum
Jul 1, 1999·Archives of Internal Medicine·O D ScheinS West
Nov 5, 1999·The Journal of Clinical Psychiatry·F M Jacobsen, L Comas-Díaz
Apr 12, 2000·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·R D Cannon, W L Chaffin
May 2, 2000·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·P WardeB Cummings
Apr 12, 2002·Journal of the American Geriatrics Society·Jonathan A ShipBruce J Baum
May 10, 2002·Community Dentistry and Oral Epidemiology·W Murray ThomsonJane M Chalmers
Jan 1, 2004·Journal of Public Health Dentistry·David Locker, P Finbarr Allen
Jun 7, 2005·Gerodontology·W Murray Thomson

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Citations

Apr 12, 2012·BMC Microbiology·Hongyu WuQingshan Huang
Dec 5, 2012·Dental Materials Journal·Hiroshi KanoHiroshi Murata
Sep 23, 2014·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Scott S De RossiStephen Hsu
Jun 4, 2013·Medicina clínica·José López-LópezEduardo Chimenos Küstner
Aug 13, 2010·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Roberto MarinoFrancesco Spadari
Feb 28, 2013·Australian Dental Journal·F Dost, C S Farah
Jul 7, 2011·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Pelin GüneriMustafa Ateş
Sep 29, 2011·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Pia López-JornetConsuelo Rodriguez-Aguado
Oct 19, 2016·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Mamoru MurakamiMasahiro Nishimura
Aug 1, 2015·Journal of Maxillofacial and Oral Surgery·R C LapiedraM D Turner
Jan 27, 2015·Clinical Oral Investigations·Ivana SkrinjarDanko Velimir Vrdoljak
Oct 11, 2014·The Journal of Prosthetic Dentistry·Fumi MizuhashiHiromi Shimomura
Jun 15, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Natascia BruniFranco Dosio
Jan 27, 2015·Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology·Michel SalomStéphane Mouly
Aug 24, 2016·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Anabel Navarro MorantePia López-Jornet
Apr 24, 2013·Contemporary Clinical Trials·Beatrice M StefanescuAvinash K Shetty
Feb 27, 2016·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Mamoru MurakamiMasahiro Nishimura
Dec 14, 2011·The Cochrane Database of Systematic Reviews·Susan FurnessRoddy McMillan
Jun 30, 2018·Gerodontology·Fernanda G SalumKaren Cherubini
Jan 27, 2009·American Journal of Respiratory Cell and Molecular Biology·Sophie Moreau-MarquisBruce A Stanton
Feb 26, 2020·Antimicrobial Agents and Chemotherapy·Kenya E FernandesDee A Carter
Feb 1, 2017·Molecular Medicine Reports·Sarra SebaaPhilippe Courtois
Sep 8, 2017·Microbiology and Immunology·Manabu NakanoShouji Hironaka
Mar 28, 2020·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Luigi RosaPiera Valenti
Dec 7, 2016·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Margarita MartínLaura Cerezo
Jun 3, 2020·The Journal of Prosthetic Dentistry·Fumi MizuhashiShuji Toya

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