Evaluation of the Content Validity and Cross-Cultural Validity of the Study Participant Feedback Questionnaire (SPFQ).

Therapeutic Innovation & Regulatory Science
Alison GreeneAdam Gater

Abstract

The Study Participant Feedback Questionnaire (SPFQ) is a patient-completed tool designed to assess patient experiences and satisfaction with aspects associated with being involved in a clinical trial. Originally developed in oncology and among English-speaking participants, the aim of the current study was to evaluate the content and cross-cultural validity of the SPFQ in other indications and non-English-speaking countries. Semi-structured qualitative telephone interviews were conducted with 80 participants across eight non-English-speaking countries (in Europe, South America and Asia) who had received an investigational medicinal product as part of a clinical trial in the past three years. Interviews comprised concept elicitation to identify concepts of importance to participants' trial experiences, and cognitive debriefing to assess understanding and perceived importance of SPFQ instructions, items and response options. Concept elicitation findings supported the content validity of the SPFQ. During cognitive debriefing, SPFQ instructions and the majority of items were well understood by participants. Participants generally considered the SPFQ items important to their clinical trial experience, albeit a handful of items asses...Continue Reading

References

Jun 5, 2007·Journal of Cancer Education : the Official Journal of the American Association for Cancer Education·Jennifer M JonesPamela Catton
Jun 1, 2010·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Kathryn Eilene LaschKathleen Rosa
Feb 27, 2014·BMC Health Services Research·Juan Pablo DomecqMohammad Hassan Murad
Jun 28, 2014·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·C Daniel MullinsPaul Wicks
Sep 10, 2014·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Kirstie HaywoodSophie Staniszewska
Jan 7, 2015·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Lori FrankSarah Daugherty
Nov 5, 2015·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·I MazarA Shields
May 14, 2016·Patient Preference and Adherence·José A SacristánAngeles Flores
Nov 1, 2014·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·E BrohanS Manson
Oct 8, 2016·Trials·Bethann Mangel PflugeisenPaul J Amoroso
Mar 1, 2017·BMC Health Services Research·Pronabesh DasMahapatraPaul Wicks
Mar 16, 2017·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·John R KirwanSusan J Bartlett
Sep 21, 2018·Therapeutic Innovation & Regulatory Science·Julie DietrichKelsey Jakee
Oct 23, 2018·Clinical and Translational Radiation Oncology·Kerstin A KesselStephanie E Combs
Jul 4, 2020·Therapeutic Innovation & Regulatory Science·UNKNOWN TransCelerate Biopharma Toolkits Core TeamStephen Yates

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