Evaluation of the cultivation age of dried ginseng radix and its commercial products by using (1)H-NMR fingerprint analysis

The American Journal of Chinese Medicine
Wen-Neng LinWen-Te Chang

Abstract

The perfect ginseng radix is collected when the ginseng root reaches a cultivation age of six years; this ensures the best mass quality and consistency of the plant's essential bioactive components. Since traditional means of authentication via physical appearance or smell are hardly reliable, an efficient analytical method that can determine the real cultivation age of dried ginseng radix in commercial products, especially ginseng products of various dosage forms, is urgently required. In the present study, chemical fingerprint by (1)H-NMR spectroscopy was used on dried ginseng radix samples with cultivation ages ranging from 1-6 years. The resulting dataset was then analyzed by using principle component analysis and cluster analysis to build up a distributive model that allows the identification of the real cultivation age of the ginseng radix based on a plant metabolomic strategy. This quality surveillance method was able to clearly discriminate the 6 years old ginseng radix from the other ages, and could be applied on the evaluation of the real cultivation age for the various dried white ginseng radix samples and commercial products accurately.

References

Dec 1, 1994·Journal of Ethnopharmacology·A GrandhiB Patwardhan
Dec 19, 2001·Journal of Korean Medical Science·T K Yun
Jan 7, 2005·Chemical & Pharmaceutical Bulletin·Hye Kyong KimRobert Verpoorte
Feb 17, 2005·Journal of Agricultural and Food Chemistry·Young Hae ChoiRobert Verpoorte
Sep 25, 2007·Phytochemical Analysis : PCA·Cristina DaolioMárcia M C Ferreira

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Citations

Nov 22, 2011·Journal of Natural Medicines·Tyler CalwayChun-Su Yuan
Jan 25, 2011·Natural Product Reports·Lian-Wen QiChun-Su Yuan
Mar 30, 2013·Plant Physiology and Biochemistry : PPB·Rui MaDaqing Zhao
Nov 1, 2011·Journal of Ginseng Research·Si-Kwan Kim, Jeong Hill Park
Mar 2, 2011·Journal of Ginseng Research·Chun-Su YuanLian-Wen Qi
Jul 6, 2010·Biochemical Pharmacology·Lian-Wen QiChun-Su Yuan
Jul 2, 2011·The American Journal of Chinese Medicine·Po-Chuen ChanPeter P Fu
Aug 30, 2012·The American Journal of Chinese Medicine·Tse-Yu ChungJason T C Tzen
Dec 12, 2012·The American Journal of Chinese Medicine·Tian WangWenyan Xie
Aug 21, 2010·Journal of Food Science·So-Hyun KimBoo-Yong Lee
Jul 8, 2016·Chemical & Pharmaceutical Bulletin·Jung-Sub ShinJongheon Shin
Nov 19, 2017·Plant Cell Reports·Yu-Jin KimDabing Zhang
Jun 30, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Dahye YoonDae Young Lee
Jan 29, 2021·Frontiers in Pharmacology·Mihael Cristin Ichim, Hugo J de Boer
May 4, 2021·Frontiers in Pharmacology·Mihael Cristin Ichim, Anthony Booker
Sep 16, 2011·Journal of Agricultural and Food Chemistry·Nahyun KimDongho Lee

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