Evaluation of the de-selection of men who have had sex with men from blood donation in England

Vox Sanguinis
K Soldan, K Sinka

Abstract

The Blood Services of the UK permanently de-select men who have had sex with men (MSM) from donating blood. The rationale for this has been questioned. This article attempts to evaluate whether this selection criterion does contribute to blood safety. Data about transfusion-transmissible infections, in particular about human immunodeficiency virus (HIV) infection, were used to evaluate whether de-selection of MSM meets the aims of donor selection. Models were constructed to estimate the risk of HIV-infectious donations entering the blood supply should this criterion be changed. Many assumptions were required to generate estimates of the risk of HIV infection entering the blood supply. The accuracy of the estimates is therefore uncertain and the probable ranges around the estimates were wide. However, by using the most probable assumptions, our models suggested that de-selection of MSM for 12 months since the last sexual contact, or complete removal of this selection criterion, would be expected to increase the risk of HIV-infectious donations entering the blood supply in England by approximately 60% (from the current risk of 0.45 per year to 0.75 per year) and 500% (to 2.5 per year), respectively. The increase in numbers of non...Continue Reading

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Citations

Feb 5, 2010·The American Journal of Bioethics : AJOB·Anthony Vernillo
Apr 26, 2007·AIDS·Giedrius LikataviciusAnthony Nardone
Jan 1, 2012·Journal of Blood Transfusion·Jay P Brooks
Oct 25, 2011·American Journal of Public Health·Susan M Kansagra, Thomas A Farley
Dec 1, 2011·Transfusion Medicine Reviews·Nicholas A WatkinsMarc L Turner
Sep 29, 2011·Transfusion Medicine Reviews·Sheila F O'BrienSteven H Kleinman
Mar 15, 2011·Transfusion clinique et biologique : journal de la Société française de transfusion sanguine·J Pillonel, C Semaille
Apr 26, 2008·Clinics in Laboratory Medicine·Jay P Brooks
Dec 8, 2007·Transfusion Medicine Reviews·William LeissDaniel Krewski
Mar 9, 2005·Transfusion·Ana M SanchezUNKNOWN Retrovirus Epidemiology Donor Study
Feb 19, 2008·Transfusion Medicine·J A MustoJ M Kaldor
Jun 15, 2007·Transfusion Medicine·Ian M Franklin
Jun 23, 2011·Vox Sanguinis·J PillonelUNKNOWN Blood Donor Epidemiological Surveillance Study Group
Jan 15, 2014·Transfusion·Walter LiszewskiNicholas Van Sickels
Jul 22, 2014·Vox Sanguinis·R OffergeldM-E Behr-Gross
Dec 22, 2017·Transfusion·Bas RomeijnAnne van Dongen
Aug 3, 2019·Vox Sanguinis·Katy L DavisonUNKNOWN the Surveillance, Risk Assessment, Policy Sub-Group of the ISBT Transfusion Transmitted Diseases Working Party
Oct 18, 2016·Current Opinion in Hematology·Mindy Goldman, Sheila F O'Brien
Dec 22, 2016·Israel Journal of Health Policy Research·Gary Michael GinsbergDaniel Chemtob

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