Evaluation of the Effect of Cumulative Operator Experience on Hepatocellular Carcinoma Recurrence after Primary Treatment with Radiofrequency Ablation

Radiology
Teng-Yu LeeChun-Ying Wu

Abstract

To investigate the association between cumulative operator volume and the risk of hepatocellular carcinoma (HCC) recurrence after potentially curative radiofrequency ablation (RFA). This study was approved by the Research Ethics Committee. By using the Taiwan National Health Insurance Research Database, 52 096 patients with HCC were identified between July 1, 2004, and December 31, 2011. In total, 2827 patients were selected who underwent potentially curative RFA for newly diagnosed HCC. These patients were grouped into quintiles according to the cumulative operator volumes. Patients in the lowest or the highest quintiles were 1:1 matched according to their propensity scores. Finally, two separate groups, each containing 406 patients, were recruited in the high- and low-volume groups (cumulative operator volume of ≥79 cases and ≤10 cases, respectively). Cumulative incidences of and hazard ratios for HCC recurrence were analyzed after adjusting for competing mortality. The HCC recurrence rate of the high-volume group was significantly lower than that of the low-volume group (high-volume group 5-year recurrence rate of 65.8%, 95% confidence interval [CI]: 59.5%, 72.1%; low-volume group 5-year recurrence rate of 71.4%, 95% CI: 66....Continue Reading

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Citations

Oct 2, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Teng-Yu LeeChun-Ying Wu
Aug 30, 2016·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Jianfeng WangXiaoming Yang
Sep 30, 2016·The British Journal of Surgery·T NishigoriY Sakai
Apr 28, 2018·AJR. American Journal of Roentgenology·Jeffrey L Weinstein, Muneeb Ahmed
Jan 5, 2017·Cardiovascular and Interventional Radiology·F Edward BoasStephen B Solomon
Dec 18, 2020·Seminars in Interventional Radiology·Jeffrey L Weinstein, Muneeb Ahmed

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