Evaluation of the effect of probiotics in the treatment of peri-implant mucositis: a triple-blind randomized clinical trial

Clinical Oral Investigations
Marta PeñaJosé Nart

Abstract

To determine if the treatment of mucositis with mechanical debridement, 0.12% chlorhexidine, and a further application of Lactobacillus reuteri (L. reuteri) will result in an improvement of the clinical and microbiological parameters in comparison to the treatment with mechanical debridement and 0.12% chlorhexidine alone. Fifty dental implants with mucositis in 50 patients were randomly assigned to one of the following groups: mechanical debridement, 0.12% chlorhexidine mouthwash, and the subsequent administration of a probiotic agent (test group) or mechanical debridement and 0.12% chlorhexidine mouthwash (control group). Data were analyzed to determine clinical and microbiological changes during treatment and after a follow-up period of 3 months. After the administration of 0.12% chlorhexidine, all clinical parameters improved in the test and the control group, observing a significant decrease in Full Mouth Plaque Index (FMPI), full mouth bleeding on probing (FMBOP), Plaque Index (PI), and bleeding on probing (BOP) at the implant. However, following the administration of probiotics or placebo, the clinical variables, except for probing pocket depth, slightly and progressively increased up to 3 months of follow-up, but without...Continue Reading

References

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Citations

Nov 11, 2019·Clinical Oral Implants Research·Isabelle LalemanWim Teughels
Jan 17, 2021·American Journal of Otolaryngology·Alexandra T Bourdillon, Heather A Edwards
Mar 6, 2021·PloS One·Paul Mathias JansenGeorg Conrads
Aug 31, 2021·The Journal of Pain : Official Journal of the American Pain Society·Dan WangLaura A Frey-Law

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