Evaluation of the HemoCue plasma haemoglobin analyser for assessing haemolysis in red cell concentrates during storage

Vox Sanguinis
Rebecca Cardigan, K Smith

Abstract

To evaluate the HemoCue plasma haemoglobin (Hb) analyser for determining supernatant Hb in red cell concentrates (RCC) during storage and compare this to a spectrophotometric method. Samples from RCC (n = 20) at days 0, 7, 21, 35 and 42 of storage were tested by both methods for supernatant Hb. Results are given as median with range. There was a significant correlation (r = 0.97, P < 0.0001), but statistically significant difference between the two methods (0.72 (0.36-2.77) spectrophotometric vs. 0.70 (0.3-2.6) g/l HemoCue). However, the mean bias was negligible at 0.06 g/l. The HemoCue method gave a interassay coefficient of variation of 5.6% at 1.2 g/l and was linear to at least 20 g/l. The HemoCue plasma haemoglobin analyser is a simple, rapid, reliable and accurate method for the determination of supernatant Hb in RCC at the end of storage and compares well to established methods for supernatant Hb measurement.

References

Jul 4, 2001·Psychiatric Services : a Journal of the American Psychiatric Association·UNKNOWN Committe on Psychiatry and the Community of the Group for the Advancement of Psychiatry

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Citations

May 17, 2011·Asian Journal of Transfusion Science·R N MakrooN L Rosamma
Jan 26, 2007·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Manish J GandhiThomas H Price
Jun 5, 2019·Annals of the New York Academy of Sciences·Ralph D WhiteheadMaria Elena D Jefferds
Jul 19, 2013·Journal of the American Animal Hospital Association·Bérénice ConversyJulie Beaudoin
Jun 21, 2021·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Nicolas MalvauxMarcia Cardoso

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