PMID: 24351533Dec 20, 2013Paper

Evaluation of the heterogeneity of systematic reviews on nutrition support for burn patients with Meta-regression algorithm

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns
Bin CaiJun Zeng

Abstract

To evaluate the heterogeneity of systematic reviews (SRs) on nutrition support for burn patients with Meta-regression algorithm quantitatively. SRs on nutrition support for burn patients since 1980 were searched in 7 databases, including PubMed, EMBASE on CD, Science Citation Index, Cochrane Library, Chinese Biomedicine Database, Chinese Medical Current Contents, and Chinese Journal Full-text Database. SRs were identified with inclusion criteria: the research was interventive SR or Meta analysis of clinical data of burn patients aged equal to or over 18 years who had received clinical nutrition intervention, with regimen including special nutrient given including enterally or parenterally; the outcome indicator was mortality. A two-step method was established to evaluate the heterogeneity of SRs. (1) Qualitative analysis: the publication time of SRs and the trial design, patient type, regimen or route of nutrition therapy, energy intake, and outcome reported by the included clinical trial were analyzed. (2) Quantitative analysis: a mortality Meta-regression model was established by trial design, publication time, regimen or route of nutrition therapy, and energy intake to calculate the expected mortality. Observation/expectatio...Continue Reading

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