PMID: 19142446Jan 15, 2009Paper

Evaluation of the humoral immune response to Strongyloides venezuelensis antigens

Revista Da Sociedade Brasileira De Medicina Tropical
Carla Rodrigues RigoV Amato Neto

Abstract

Strongyloidiasis affects 30 million people in 70 countries. This enteral parasitosis is usually diagnosed using parasitological tests based on hydrotropism or thermotropism of larvae eliminated in feces, but these tests have been shown to have low sensitivity. In this study, antigenic extracts were tested by means of ELISA, immunoblotting and IFI, using filariform larvae of Strongyloides venezuelensis, a parasite of rodents that shows cross-reactions with Strongyloides stercoralis epitopes. Sensitivity of 89, 85 and 57% for the ELISA reaction and 100, 100 and 96% for immunoblotting with the SAL, ZWIP and ZW antigens, and specificity of 90, 60 and 81% for ELISA and 96, 92 and 91% for immunoblotting with the same antigens, were found in these assays.

References

Jan 1, 1991·Journal of Clinical Laboratory Analysis·D S GridleyJ M Tosk
May 1, 1990·Transactions of the Royal Society of Tropical Medicine and Hygiene·Y SatoY Shiroma
May 1, 1990·International Journal for Parasitology·C Northern, D I Grove
Jan 1, 1985·Transactions of the Royal Society of Tropical Medicine and Hygiene·Y SatoM Otsuru
Sep 1, 1980·The Journal of Clinical Investigation·N J DollJ E Salvaggio
Mar 1, 1981·The American Journal of Tropical Medicine and Hygiene·D I Grove, A J Blair
Apr 1, 1993·Revista Da Sociedade Brasileira De Medicina Tropical·C L RossiR C Trevisan
May 22, 2001·AIDS Patient Care and STDs·R SarangarajanV Tchertkoff
Jul 4, 2001·QJM : Monthly Journal of the Association of Physicians·P R SánchezC R Olmos
Aug 31, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A A Siddiqui, S L Berk
Dec 7, 2002·Molecular and Biochemical Parasitology·Varatharajalu RaviFranklin A Neva
Jan 30, 2008·Experimental Parasitology·Eleuza Rodrigues MachadoMarlene Tiduko Ueta

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.