Evaluation of the impact of light scatter from glistenings in pseudophakic eyes

Journal of Cataract and Refractive Surgery
Edward DeHoog, Anand Doraiswamy

Abstract

To study the impact of light scatter from glistenings in pseudophakic eyes using ray tracing in a model eye Department of Research, Advanced Vision Science, Inc., Goleta, California, USA. Mathematical modeling and simulation. A pseudophakic eye model was constructed in Zemax using the Arizona eye model as the basis. The Mie scattering theory was used to describe the intensity and direction of light as it scatters for a spherical particle immersed in a given media (intraocular lens [IOL]). The modeling and evaluation of scatter and modulation transfer function (MTF) were performed for several biomaterials with various size and density of glistenings under scotopic, mesopic, and photopic conditions. As predicted by the Mie theory, the amount of scatter was a function of the relative difference in refractive index between the media and the scatterer, the size of the scatterer, and the volume fraction of the scatterer. The simulation demonstrated that an increase in density of glistenings can lead to a significant drop in the MTF of the IOL and the pseudophakic eye. This effect was more pronounced in IOLs with smaller cavitations, and the observation was consistent for all tested biomaterials. Mathematical modeling demonstrated tha...Continue Reading

References

Aug 1, 1995·American Journal of Ophthalmology·J E GreivenkampM D Mellinger
Jul 1, 1993·Journal of the Optical Society of America. A, Optics and Image Science·A J LangV Portney
Jul 1, 1993·Journal of Cataract and Refractive Surgery·A Lang, V Portney
Jan 1, 1996·Journal of Cataract and Refractive Surgery·T OshikaS Yaguchi
May 1, 1996·Journal of Cataract and Refractive Surgery·D K DhaliwalO Omar
Mar 12, 1998·Journal of Cataract and Refractive Surgery·O OmarR J Olson
May 30, 2001·Journal of Cataract and Refractive Surgery·G ChristiansenK Christiansen
Nov 1, 2001·Journal of Cataract and Refractive Surgery·U GunencM Ferliel
Aug 6, 2003·Journal of Cataract and Refractive Surgery·Hitoshi NishiharaMasahiko Ayaki
Nov 8, 2003·Journal of Cataract and Refractive Surgery·Javier Moreno-MontañésAna Fernández-Hortelano
May 12, 2004·Journal of Vision·Jason D MarsackRaymond A Applegate
Apr 3, 2007·Journal of Cataract and Refractive Surgery·Liliana Werner
Jul 3, 2007·American Journal of Ophthalmology·Aaron WaiteRandall J Olson
Jul 3, 2008·Applied Optics·Guang-Ming Dai, Virendra N Mahajan
Dec 23, 2008·Journal of Cataract and Refractive Surgery·Anders Behndig, Eva Mönestam
Jul 28, 2009·Journal of Cataract and Refractive Surgery·Richard J Mackool, Joseph Colin
Aug 29, 2009·Acta Biomaterialia·David M SaylorSteven K Pollack
Nov 3, 2009·Journal of Cataract and Refractive Surgery·Hiroyuki MatsushimaTadashi Senoo
Jul 27, 2010·Journal of Cataract and Refractive Surgery·Liliana Werner
Aug 31, 2010·Journal of Biomedical Optics·Henk A WeeberPatricia A Piers
Nov 30, 2010·Journal of Cataract and Refractive Surgery·Mayumi NagataShinichiro Yoshida
Feb 11, 2012·Journal of Cataract and Refractive Surgery·Kazunori MiyataKeiichiro Minami
May 29, 2012·American Journal of Ophthalmology·Ken HayashiHideyuki Hayashi
Jun 26, 2012·Journal of Cataract and Refractive Surgery·Nick Mamalis
Jun 26, 2012·Journal of Cataract and Refractive Surgery·Joseph ColinCedric Schweitzer
Sep 25, 2012·Journal of Cataract and Refractive Surgery·Marcia D OngMutlu Karakelle

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Citations

Jan 23, 2016·Journal of Cataract and Refractive Surgery·Heike BiwerThomas Kohnen
Jul 21, 2015·Journal of Cataract and Refractive Surgery·Bradley S HenriksenRandall J Olson
Dec 4, 2014·Journal of Cataract and Refractive Surgery·Yoriko TakahashiHiroshi Sasaki
Apr 27, 2016·Journal of Cataract and Refractive Surgery·Edward DeHoog, Anand Doraiswamy
Jul 5, 2016·Journal of Cataract and Refractive Surgery·Eva Mönestam, Anders Behndig
Aug 20, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Youngsub EomHyo Myung Kim
Oct 5, 2016·Journal of Cataract and Refractive Surgery·Béatrice Cochener, UNKNOWN Concerto Study Group
Feb 13, 2020·Journal of Cataract and Refractive Surgery·Tetsuro OshikaKazunori Miyata
Mar 21, 2017·Journal of Cataract and Refractive Surgery·Grzegorz ŁabuzThomas J T P van den Berg
Nov 11, 2020·Journal of Refractive Surgery·Youngsub EomHyo Myung Kim
Nov 10, 2020·Current Opinion in Ophthalmology·Piotr KanclerzRamin Khoramnia
May 3, 2020·Journal of Cataract and Refractive Surgery·Tetsuro OshikaKazunori Miyata

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