Evaluation of the Incidence and Potential Mechanisms of Tracheal Complications in Patients With COVID-19.

JAMA Otolaryngology-- Head & Neck Surgery
Giacomo FiacchiniLuca Bruschini

Abstract

Full-thickness tracheal lesions and tracheoesophageal fistulas are severe complications of invasive mechanical ventilation. The incidence of tracheal complications in ventilated patients with coronavirus disease 2019 (COVID-19) is unknown. To evaluate whether patients with COVID-19 have a higher incidence of full-thickness tracheal lesions and tracheoesophageal fistulas than matched controls and to investigate potential mechanisms. This is a retrospective cohort study in patients admitted to the intensive care unit in a tertiary referral hospital. Among 98 consecutive patients with COVID-19 with severe respiratory failure, 30 underwent prolonged (≥14 days) invasive mechanical ventilation and were included in the COVID-19 group. The control group included 45 patients without COVID-19. Patients with COVID-19 were selected from March 1 to May 31, 2020, while the control group was selected from March 1 to May 31, 2019. Patients with COVID-19 had severe acute respiratory syndrome coronavirus 2 infection diagnosed by nasopharyngeal/oropharyngeal swabs and were treated according to local therapeutic procedures. The primary study outcome was the incidence of full-thickness tracheal lesions or tracheoesophageal fistulas in patients with...Continue Reading

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Citations

Feb 12, 2021·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Giacomo FiacchiniLuca Bruschini
Feb 6, 2021·American Journal of Otolaryngology·Vinciya PandianMichael J Brenner
Feb 26, 2021·JAMA Otolaryngology-- Head & Neck Surgery·Karthik BalakrishnanAlexander T Hillel
Mar 9, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Alessandro BellettiUNKNOWN COVID-BioB Study Group
Mar 26, 2021·JAMA Otolaryngology-- Head & Neck Surgery·Christopher H RassekhMichael J Brenner
Mar 3, 2021·Chest·Michael J BrennerJose De Cardenas
Apr 23, 2021·JAMA Otolaryngology-- Head & Neck Surgery·Brendan A McGrathMichael J Brenner
Jun 10, 2021·Clinical Medicine Insights. Case Reports·Kishore Sandu
Aug 8, 2021·Respiratory Medicine·Alessandro BellettiAlberto Zangrillo
Aug 22, 2021·BMJ Case Reports·Patricia Maria Gregoria Mina CuañoRalph Elvi Villalobos
Aug 31, 2021·OTO Open : the Official Open Access Journal of the American Academy of Otolaryngology--Head and Neck Surgery Foundation·Andrew J NeevelAndrew P Stein
Oct 5, 2021·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Patrick Alexander WardUNKNOWN Chelwest COVID-19 Tracheostomy Group

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