Evaluation of the microbial growth response to inorganic nanoparticles

Journal of Nanobiotechnology
Darryl N WilliamsTracey R Pulliam Holoman

Abstract

In order to enhance the utilization of inorganic nanoparticles in biological systems, it is important to develop a fundamental understanding of the influence they have on cellular health and function. Experiments were conducted to test silica, silica/iron oxide, and gold nanoparticles for their effects on the growth and activity of Escherichia coli (E. coli). Transmission electron microscopy (TEM) and dynamic light scattering (DLS) were used to characterize the morphology and quantify size distribution of the nanoparticles, respectively. TEM was also used to verify the interactions between composite iron oxide nanoparticles and E. coli. The results from DLS indicated that the inorganic nanoparticles formed small aggregates in the growth media. Growth studies measured the influence of the nanoparticles on cell proliferation at various concentrations, showing that the growth of E. coli in media containing the nanoparticles indicated no overt signs of toxicity.

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Citations

Jan 1, 2008·Journal of Nanobiotechnology·Mikhail Soloviev
Jan 1, 2009·Nanoscale Research Letters·G L BuryginN G Khlebtsov
Aug 7, 2013·Nanotoxicology·Nawel Ould-MoussaJean-François Berret
Jul 21, 2015·Chemical Society Reviews·Kristen P MillerAlan W Decho
Sep 11, 2012·Journal of Basic Microbiology·Saranya SugumarNatarajan Chandrasekaran
Jun 3, 2015·Environmental Toxicology and Chemistry·Sebastian HössWalter Traunspurger
Oct 1, 2011·Chemical Communications : Chem Comm·Abdul HameedShamsa Kanwal
Jul 14, 2012·Chemical & Pharmaceutical Bulletin·Mahesh Kumar TalariMinaketan Tripathy
Jul 14, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·K GiannousiC Dendrinou-Samara
May 7, 2015·Environmental Science and Pollution Research International·Nandita DasguptaAshutosh Kumar
Dec 18, 2013·Biotechnology and Applied Biochemistry·Suriyaprabha RangarajKannan Narayanasamy
Jul 4, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·B ChanteauJ-F Berret
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Jun 28, 2019·Environmental Science & Technology·Chenchen QuQiaoyun Huang
Aug 28, 2018·Langmuir : the ACS Journal of Surfaces and Colloids·Anna PerdikakiGeorgios N Karanikolos

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Methods Mentioned

BETA
transfect
dynamic light scattering

Software Mentioned

Photocor

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