Evaluation of the nature, severity, likelihood and preventability of medication-related hospital-acquired complications.

Australian Health Review : a Publication of the Australian Hospital Association
Martin CanningErin Dunn

Abstract

Objective Pricing for safety and quality was introduced into Australian hospitals using a defined list of hospital-acquired complications (HACs). Medication-related HACs include drug-related respiratory complications (DRRC), haemorrhagic disorder due to circulating anticoagulants (HDDCA) and hypoglycaemia. The aim of this study was to determine the probability, severity and preventability of medication-related HACs, common contributory medications and themes, and whether medication-related HACs are a suitable data source to inform risk associated with medicines use. Methods Medical notes were reviewed retrospectively for all patients discharged from a tertiary referral metropolitan hospital between 1 July and 31 December 2018 who were flagged as experiencing a medication-related HAC. Naranjo, Hartwig's and Schumock and Thornton tools were used to assess the probability, severity and preventability of medication-related HACs. Results Over the 6-month period, 88 patients experienced a medication-related HAC. An HAC was not identified in five (5.7%) patient charts. The most common HAC was hypoglycaemia (n=59; 67%), followed by HDDCA (n=23; 26%) and DRRC (n=6; 7%). Fifteen patients (17%) flagged with a hypoglycaemia HAC were not on...Continue Reading

References

Aug 1, 1981·Clinical Pharmacology and Therapeutics·C A NaranjoD J Greenblatt
Nov 17, 2009·The Medical Journal of Australia·Terri J JacksonJohn G Wakefield
Oct 12, 2010·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Robin E Ferner, Jeffrey K Aronson
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Oct 12, 2012·The New England Journal of Medicine·Grace M LeeAshish K Jha
Nov 14, 2013·Journal of the American Medical Informatics Association : JAMIA·Corinne M HohlJürgen Stausberg
Dec 20, 2013·Australian Health Review : a Publication of the Australian Hospital Association·Alexandra L PhillipsSepehr Shakib
May 30, 2014·Australian Health Review : a Publication of the Australian Hospital Association·Sumit ParikhTerri Jackson
Jan 15, 2015·International Journal for Quality in Health Care : Journal of the International Society for Quality in Health Care·Johanna I WestbrookRichard O Day
Dec 27, 2016·Annals of Internal Medicine·Jason H WasfyRobert W Yeh
Apr 7, 2017·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Nibu Parameswaran NairLuke R Bereznicki
Jul 20, 2018·Health Services Research·Caroline P ThirukumaranYue Li
Oct 13, 2018·European Journal of Clinical Pharmacology·Nazanin FalconerNeil Cottrell

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