Evaluation of the pattern of liver tests and yield of cholangiography in symptomatic choledocholithiasis: a prospective study

Gastrointestinal Endoscopy
A D Roston, I M Jacobson

Abstract

The role of ERCP in the management of choledocholithiasis in an era of minimally invasive therapy continues to be defined. We evaluated prospectively the pattern of liver test abnormalities and yield of cholangiography after presentation with illnesses suggesting choledocholithiasis. Ninety-four consecutive patients, all with liver test abnormalities (total bilirubin, alkaline phosphatase, AST, and ALT) at presentation, had serial determinations to within 24 hours of cholangiography and were divided into four groups based on their patterns of rise or fall of liver test results as well as presenting clinical syndrome. Group I: normalized liver tests; Group II: falling liver tests, and alkaline phosphatase falling greater than 50% of the difference between presentation value and upper limit of normal; Group III: alkaline phosphatase falling less than 50%; and Group IV: any liver test with increasing levels. Clinical syndromes included cholangitis, pancreatitis, combined cholangitis and pancreatitis, and biliary pain with abnormal liver tests. Yields of choledocholithiasis were 13% (Group I), 50% (Group II), 67% (Group III), and 94% (Group IV). Yield by syndromes were 36% (biliary pancreatitis), 72% (biliary pain and abnormal live...Continue Reading

References

May 1, 1986·Digestive Diseases and Sciences·M L AnciauxJ P Etienne
Feb 1, 1983·Radiology·J J CronanJ T Ferrucci

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Citations

Sep 26, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Dana A TelemCelia M Divino
Dec 10, 1999·European Journal of Ultrasound : Official Journal of the European Federation of Societies for Ultrasound in Medicine and Biology·E Buscarini, L Buscarini
Dec 16, 1998·Journal of the American College of Surgeons·R GolubM Tan
Dec 10, 1999·The New England Journal of Medicine·W R Brugge, J Van Dam
Apr 18, 2012·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Majid A AlmadiAlan N Barkun
Oct 13, 2011·ISRN Gastroenterology·Bülent GüngörZafer Malazgirt
May 26, 2001·Gastrointestinal Endoscopy·G M EisenUNKNOWN American Society for Gastrointestinal Endoscopy. Standards of Practice Committee
Mar 12, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Frances TseAlan N Barkun
Jun 23, 2012·Journal of the Chinese Medical Association : JCMA·Lien-Fu Lin, Pi-Teh Huang
Sep 14, 2010·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Ala I ShararaMustapha El Halabi
Jan 30, 2008·Gastrointestinal Endoscopy·Frances TsePaul Moayyedi
Nov 28, 2006·Best Practice & Research. Clinical Gastroenterology·Grant R Caddy, Tony C K Tham
Jan 5, 2002·The American Journal of Gastroenterology·M E CohenM Topazian
Feb 27, 2015·The Cochrane Database of Systematic Reviews·Kurinchi Selvan GurusamyBrian R Davidson
Feb 27, 2015·The Cochrane Database of Systematic Reviews·Vanja GiljacaBrian R Davidson
Feb 27, 2015·The Cochrane Database of Systematic Reviews·Kurinchi Selvan GurusamyBrian R Davidson
Oct 13, 2006·The American Journal of Gastroenterology·Peter A BanksUNKNOWN Practice Parameters Committee of the American College of Gastroenterology

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