Evaluation of the polyethylene glycol-potentiated indirect antiglobulin test

Transfusion
B WenzD P Shah

Abstract

Results of the indirect antiglobulin test (IAT) potentiated by the addition of polyethylene glycol (PEG) were compared with those of the IAT performed with bovine serum albumin (BSA). This retrospective study, which encompasses 3 years, confirms that use of PEG-IAT increases the rate of detection of clinically significant red cell (RBC) antibodies, decreases the detection of insignificant antibodies, reduces the need to use other serologic enhancement techniques (such as enzyme modification of RBCs), and has a positive impact on the laboratory's workload. These advantages are provided with no diminution in the quality of service provided by the blood bank.

Citations

Jun 1, 2009·Indian Journal of Hematology & Blood Transfusion : an Official Journal of Indian Society of Hematology and Blood Transfusion·Jalada PatelSnehalata Gupte
Oct 19, 2001·Transfusion·B DiedrichA Shanwell
Aug 15, 2006·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Denis M DwyreRonald G Strauss
May 13, 1999·Immunopharmacology and Immunotoxicology·A MorioN Watanabe

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