Evaluation of the population distribution of dietary contaminant exposure in an Arctic population using Monte Carlo statistics

Environmental Health Perspectives
H M ChanH V Kuhnlein

Abstract

Organochlorines and heavy metals have bioaccumulated in Arctic wildlife, which is an important food source for the Inuit. In this study, we have developed a statistical model to describe the population distribution of contaminant exposure and the usual intake of the high-end contaminant consumers. Monte Carlo methods are used to account for variations due to seasonal dietary pattern and contaminant concentrations. Distribution of the dietary intake of the contaminants of most concern-mercury, polychlorinated biphenyls (PCBs), chlordane, and toxaphenes-are described. Over 50% of the residents had dietary exposure levels exceeding the tolerable daily intake or provisional tolerable daily intake for Hg, toxaphene, and chlordane (83, 91, and 71% for men and 73, 85, and 56% for women, respectively). The high-end consumers (i.e. the 95th centile) have intake levels 6 times higher than the provisional tolerable weekly intake of Hg, and over 20 times the tolerable daily intake of chlordane and toxaphene. Assessment of health risks of the relative high contaminant exposure in this community must also consider the nutritional, economical, cultural, and social importance of these traditional foods. A comprehensive risk management scheme h...Continue Reading

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Citations

Feb 8, 2003·Environmental Health Perspectives·Timothy William LambertJohn B Dossetor
Apr 23, 2005·Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews·Arthur ChiuShawn Gerstenberger
Jun 4, 2008·Environmental Health : a Global Access Science Source·Julie FontaineSerge Déry
Nov 22, 2005·The Science of the Total Environment·J Van OostdamS Kalhok
Oct 30, 2004·Scandinavian Journal of Public Health·Peter BjerregaardSven O E Ebbesson
Jul 16, 2010·Risk Analysis : an Official Publication of the Society for Risk Analysis·Lon KissingerAnn H Williams
Dec 22, 2019·Integrated Environmental Assessment and Management·Álvaro Fernández-LlamazaresVictoria Reyes-García
Nov 14, 2020·The Science of the Total Environment·Mariana de Moraes PontualMélanie Lemire

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