Evaluation of the prognosis of fulminant viral hepatitis in late pregnancy by the MELD scoring system.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
Y YangLin Ma

Abstract

The purpose of this paper was to analyze the prognosis of women with fulminant viral hepatitis in late pregnancy (FVHILP) by the Model for End-Stage Liver Disease (MELD) scoring system. A retrospective study involving patients admitted to two tertiary hospitals between January 1, 1994 and June 30, 2011 was undertaken. The relations between MELD scores and change of MELD score over time (ΔMELD) and prognosis during hospitalization were analyzed. Among the 54 patients with FVHILP, the MELD scores on admission were significantly higher in the non-survival group than those in the survival group (p < 0.05). Among the 26 FVHILP patients who underwent cesarean section, the MELD scores before and after cesarean section were both significantly higher in the non-survival group (p < 0.05). The ΔMELD scores (before operation and three days after operation) significantly increased in the non-survival group (p < 0.05). The concordance (c-statistic) values were all greater than 0.8. The MELD scoring system shows excellent short-term predictive value for the prognosis of FVHILP.

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Citations

Aug 22, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Nancy Reau
Sep 6, 2012·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Liuzhi DengLin Ma
Jan 14, 2020·Expert Review of Gastroenterology & Hepatology·Francesco AzzaroliMaria Letizia Petroni
Oct 24, 2014·World Journal of Gastroenterology : WJG·Irina P BalmasovaChang-Lu Gao
Feb 23, 2019·Interventional Medicine & Applied Science·Mehri Seifoleslami
Aug 25, 2015·World Journal of Hepatology·Mercedes Amieva-BalmoriJosé María Remes-Troche

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