Evaluation of the relationships between intravenous patient-controlled analgesia settings and morphine requirements among patients after lumbar spine surgery

Acta Anaesthesiologica Taiwanica : Official Journal of the Taiwan Society of Anesthesiologists
Hsin-Lun WuKuang-Yi Chang

Abstract

To evaluate the association between daily morphine requirement and the intravenous patient-controlled analgesia (IVPCA) setting in patients undergoing spinal surgery. We conducted a retrospective analysis of 179 patients of American Society of Anesthesiologists physical status class I-III who underwent elective posterior lumbar spinal surgery and consented to IVPCA for postoperative pain control. The regi-mental solution contained morphine 1 mg/mL. The IVPCA program was set to deliver a priming dose of 1.5-4 mL, a basal infusion rate of 0-1.2 mL/hr, and a 0.5-1.5 mL bolus on demand with a 5-minute lockout interval. Demographic data, surgical procedures, analgesia program setting variables, 4-hour cumulative morphine dose and 11-point numeric rating scale for pain on postoperative days 1 and 2 were collected for comparison. The IVPCA requirement decreased gradually over time (p < 0.001). The number of vertebrae involved significantly influenced the daily morphine requirements (p = 0.01). None of the IVPCA settings, including continuous infusion, affected daily morphine requirements. On average, the analgesic requirement on postoperative day 2 was 18% less than that on postoperative day 1. The number of vertebrae involved was sig...Continue Reading

References

Jan 1, 1989·Anaesthesia·H OwenM J Cousins
Feb 1, 1996·Pain·P E Macintyre, D A Jarvis
Jul 20, 2001·British Journal of Anaesthesia·P E Macintyre
May 8, 2003·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Didem DalUlku Aypar
Mar 15, 2005·Anesthesiology Clinics of North America·Pamela E Macintyre
Nov 14, 2006·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Kuang-Yi ChangWen-Kuei Chang
Mar 14, 2007·Surgical Neurology·Reuven GepsteinShay Shabat
Sep 22, 2007·Anesthesiology Clinics·Jose Ortiz-Cardona, Audrée A Bendo

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Citations

Jul 31, 2019·Revista española de anestesiología y reanimación·S De Lara GonzálezX Sala-Blanch

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