Evaluation of the small-aperture intracorneal inlay: Three-year results from the cohort of the U.S. Food and Drug Administration clinical trial

Journal of Cataract and Refractive Surgery
John VukichLing Lin

Abstract

To evaluate the safety and effectiveness of the Kamra small-aperture intracorneal inlay. Centers in North America, Europe, Asia, and Australia. Prospective clinical trial. Patients with emmetropic presbyopia had intracorneal implantation of the inlay in the nondominant eye. The study comprised 507 patients with emmetropic presbyopia who were aged 45 to 60 years old. The implanted eyes exhibited 3.5 diopters of defocus range above 20/40, with 363 (87.1%) of 417 patients and 391 (93.8%) of 417 patients having 20/40 or better monocular and binocular uncorrected near visual acuity (UNVA) at 36 months, respectively. Patients implanted via a femtosecond laser pocket procedure using a spot/line setting of 6 μm × 6 μm demonstrated further improved near vision, with 131 (90.3%) of 145 patients and 137 (94.5%) of 145 of patients having 20/40 or better monocular and binocular UNVA, respectively. Uncorrected distance visual acuity 20/25 or better was maintained in 135 (93.1%) of 145 of implanted eyes and 100% (145) of 145 of implanted eyes binocularly at 36 months. Less than 1.5% of eyes had a loss of 2 or more lines of corrected distance visual acuity for 3 months or more at any time after surgery. Forty-four inlays (8.7%) were removed fr...Continue Reading

References

Oct 1, 1985·Archives of Ophthalmology·H ChengM J Noble
Feb 9, 2002·Journal of Biomedical Materials Research·M KannoS Kubota
Jul 18, 2003·Ophthalmology·Magdalena GuzowskiPaul Mitchell
Dec 24, 2005·Cornea·Charles D ReillyMark J Mannis
Dec 7, 2007·Ophthalmology·Erich H P BraunRoger F Steinert
Oct 22, 2008·American Journal of Ophthalmology·H Kaz Soong, João Baptista Malta
Jan 18, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Kathleen S KunertJens Heichel
Feb 12, 2011·Ophthalmic Research·Jens HeichelKathleen S Kunert
Oct 25, 2011·Journal of Cataract and Refractive Surgery·Orang SeyeddainAlois K Dexl
Jan 15, 2013·Journal of Refractive Surgery·Aliki N LimnopoulouIoannis G Pallikaris
Sep 26, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Eliya LevingerSamuel Levinger
May 31, 2015·American Journal of Ophthalmology·Michiel H A LugerSamuel Arba Mosquera
Mar 28, 2016·Zeitschrift für medizinische Physik·Timo EppigAchim Langenbucher

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Citations

Jul 3, 2019·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Sarah MoussaHerbert A Reitsamer
Dec 26, 2018·Journal of Cataract and Refractive Surgery·Norman RomitoNacim Bouheraoua
May 28, 2019·Journal of Cataract and Refractive Surgery·Fabien RouimiNacim Bouheraoua
Apr 30, 2019·Current Opinion in Ophthalmology·H Burkhard Dick
May 3, 2019·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·W Neil CharmanDavid A Atchison
Jul 28, 2020·Eye·Marcus AngJorge L Alió
Jan 11, 2019·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·W Neil Charman
Mar 2, 2019·Investigative Ophthalmology & Visual Science·Beau J FennerJodhbir S Mehta
Feb 2, 2021·Experimental Eye Research·Beau J FennerJodhbir S Mehta
Mar 25, 2021·Scientific Reports·Walter D FurlanJuan A Monsoriu
Jun 4, 2021·Clinical Ophthalmology·James A KatzEric Donnenfeld
Jun 26, 2021·Journal of Refractive Surgery·Marguerite B McDonaldStephen D Klyce

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