Evaluation of Three Algorithms for the Segmentation of Overlapping Cervical Cells

IEEE Journal of Biomedical and Health Informatics
Zhi LuGhassan Hamarneh

Abstract

In this paper, we introduce and evaluate the systems submitted to the first Overlapping Cervical Cytology Image Segmentation Challenge, held in conjunction with the IEEE International Symposium on Biomedical Imaging 2014. This challenge was organized to encourage the development and benchmarking of techniques capable of segmenting individual cells from overlapping cellular clumps in cervical cytology images, which is a prerequisite for the development of the next generation of computer-aided diagnosis systems for cervical cancer. In particular, these automated systems must detect and accurately segment both the nucleus and cytoplasm of each cell, even when they are clumped together and, hence, partially occluded. However, this is an unsolved problem due to the poor contrast of cytoplasm boundaries, the large variation in size and shape of cells, and the presence of debris and the large degree of cellular overlap. The challenge initially utilized a database of 16 high-resolution ( ×40 magnification) images of complex cellular fields of view, in which the isolated real cells were used to construct a database of 945 cervical cytology images synthesized with a varying number of cells and degree of overlap, in order to provide full ...Continue Reading

References

Jul 1, 1977·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·G W ZackS A Latt
Nov 4, 2004·IEEE Transactions on Pattern Analysis and Machine Intelligence·Richard Nock, Frank Nielsen
Apr 24, 1942·Science·G N Papanicolaou
Mar 20, 2008·IEEE Transactions on Systems, Man, and Cybernetics. Part B, Cybernetics : a Publication of the IEEE Systems, Man, and Cybernetics Society·Shys-Fan Yang-MaoYen-Ping Chu
Oct 19, 2010·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Marina E PlissitiAntonia Charchanti
Jul 4, 2012·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·Marina E Plissiti, Christophoros Nikou
May 20, 2014·IEEE Transactions on Medical Imaging·Masoud S Nosrati, Ghassan Hamarneh
Aug 15, 2014·IEEE Journal of Biomedical and Health Informatics·Tao GuanYunhui Liu
Jan 15, 2015·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society· Zhi LuAndrew P Bradley

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Citations

May 26, 2017·IEEE Journal of Biomedical and Health Informatics·Ling ZhangJianhua Yao
Apr 26, 2020·Cellular and Molecular Life Sciences : CMLS·Alexios-Fotios A MentisAthanasios G Papavassiliou
Oct 18, 2019·International Journal of Molecular Sciences·Teresa ConceiçãoMaria João M Vasconcelos
Nov 16, 2019·PloS One·Sumsum SunnyMoni Abraham Kuriakose
Jan 30, 2021·BMC Medical Imaging·Iram Tazim HoqueM Sohel Rahman
Jan 25, 2021·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Ruqayya AwanNasir Rajpoot
Apr 6, 2021·Computer Methods and Programs in Biomedicine·Yixiong LiangYun Du
Jun 12, 2021·Scientific Data·Mariana T RezendeAndrea G C Bianchi
Jun 27, 2021·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·André Victória MatiasAldo von Wangenheim
Sep 26, 2021·Nature Communications·Shenghua ChengXiuli Liu

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