Evaluation of two outcome prediction models on an independent database

Critical Care Medicine
R MorenoR Van Schilfgaarde

Abstract

To evaluate the performance of the New Simplified Acute Physiology Score (SAPS II) and the admission Mortality Probability Model (MPM0) in a large independent database, using formal statistical assessment. Analysis of the database of a multicenter, multinational, prospective cohort study, EURICUS-I. Eighty nine intensive care units (ICUs) from 13 European areas. Data of 16,060 patients consecutively admitted to the participating ICUs were collected during a period of 4 months. Following the original SAPS II and MPM0 criteria, the analysis excluded: patients <18 ys of age; readmissions; patients admitted with acute myocardial infarction; burns; and patients in the postoperative period after coronary artery bypass surgery. All patients with a length of stay <8 hrs were excluded from the study to keep comparability between both systems. A total of 10,027 patients were analyzed. Collection of the first 24 hrs' admission data necessary for the calculation of SAPS II and MPM0 and basic demographic statistics. Vital status at discharge from the hospital was registered. Despite having a good discriminative capability, as measured by the area under the receiver operating characteristic (ROC) curves (SAPS II: ROC = 0.822 +/- 0.005 SEM; M...Continue Reading

References

Jun 1, 1992·Chest·W A KnausD P Wagner
Feb 1, 1991·Critical Care Medicine·S W Marra, A M Oliver
Feb 1, 1991·Critical Care Medicine·J S TurnerD M Linton
Sep 23, 1988·JAMA : the Journal of the American Medical Association·M D Silverstein
Mar 1, 1986·Annals of Internal Medicine·W A KnausJ E Zimmerman
Jan 1, 1983·Critical Care Medicine·A R Keene, D J Cullen
Jan 1, 1982·American Journal of Epidemiology·S Lemeshow, D W Hosmer
Jan 1, 1981·Clinical Pharmacology and Therapeutics·M S Kramer, A R Feinstein
Nov 1, 1994·Intensive Care Medicine·I Durand-Zaleski
Feb 22, 1995·JAMA : the Journal of the American Medical Association·J R Le GallA Artigas
Jul 1, 1994·Intensive Care Medicine·A Trilla
Jun 1, 1994·Intensive & Critical Care Nursing : the Official Journal of the British Association of Critical Care Nurses·A J Leathart
Nov 24, 1993·JAMA : the Journal of the American Medical Association·S LemeshowJ Rapoport
Dec 22, 1993·JAMA : the Journal of the American Medical Association·J R Le GallF Saulnier
May 15, 1993·Annals of Internal Medicine·W A KnausE A Draper
May 1, 1996·Intensive Care Medicine·D R Goldhill, P S Withington

❮ Previous
Next ❯

Citations

Jul 2, 2008·Intensive Care Medicine·Didier LedouxPierre Damas
Jul 23, 2002·Anaesthesia·S A Ridley
Jul 22, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·R L LinsM E De Broe
Oct 17, 2013·PloS One·Juan F LucenaJorge Quiroga
Feb 18, 2016·Journal of Critical Care·Antonios KatsounasRolf Alexander Jánosi
Feb 14, 2012·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Inês AraújoPedro Póvoa
Mar 22, 2014·Scandinavian Cardiovascular Journal : SCJ·Fabian DoerrKhosro Hekmat
Dec 6, 2008·Journal of Critical Care·Yasser SakrUNKNOWN Sepsis Occurrence in Acutely Ill Patients Investigators
Jun 6, 2007·Journal of Critical Care·Ricardo Rivera-FernándezDinis Reis Miranda
Mar 15, 2008·Acta Anaesthesiologica Scandinavica·K Strand, H Flaatten
Sep 24, 2010·Journal of Evaluation in Clinical Practice·Yasser SakrKonrad Reinhart
Aug 8, 2007·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·V G HadjianastassiouL J Hands
Jan 2, 2007·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·V G HadjianastassiouL J Hands
Oct 6, 2015·PloS One·Diego Martinez-UrbistondoJuan Felipe Lucena
Oct 23, 2014·São Paulo Medical Journal = Revista Paulista De Medicina·Ary Serpa NetoEliézer Silva
Jan 7, 2000·American Journal of Medical Quality : the Official Journal of the American College of Medical Quality·T R LiedS F Hohman
May 20, 1998·Critical Care Medicine·D Teres, P Pekow
Aug 26, 1998·Critical Care Medicine·D Teres, S Lemeshow
Sep 13, 2008·Current Opinion in Critical Care·Maurizia CapuzzoJean-Roger Le Gall
Sep 13, 2008·Current Opinion in Critical Care·Jack E Zimmerman, Andrew A Kramer
Sep 13, 2008·Current Opinion in Critical Care·Thomas L HigginsBrian Nathanson
Oct 12, 2004·European Journal of Anaesthesiology·N ScholzS Felder
Apr 2, 2008·Critical Care Medicine·Marta L RenderTimothy P Hofer
Nov 21, 1998·Critical Care Medicine·J RapoportS Lemeshow
Feb 2, 2006·Clinical Chemistry·Paul Froom, Zvi Shimoni
Oct 12, 2004·European Journal of Anaesthesiology·S VosyliusJ Ivaskevicius

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