PMID: 9177870Jun 1, 1997Paper

Evaluation of vertebral volumetric vs. areal bone mineral density during growth

Bone
S M OttL Newell-Morris

Abstract

Bone mineral "density" (BMD) measured by dual-energy X-ray absorptiometry (DEXA) does not represent the volumetric density (grams per cubic centimeter), but rather the areal density (grams per square centimeter). This distinction is important during growth. The purpose of this study was to measure vertebral dimensions in cadavers of young pigtail macaques (Macaca nemestrina), and to derive equations to predict the volumetric bone density from noninvasive measurements. We measured the areal bone density by DEXA, vertebral volume by underwater weighing, mineral content by ashing, dimensions of lumbar vertebrae by calipers, and dimensions of vertebrae by radiography. Somatometric measurements of the female lumbar vertebral bodies showed that the shape changed during growth. The bone mineral content from the densitometer correlated significantly with the ash weight (r = 0.99, error 8.7%). The correlation coefficient between the volumetric bone mineral density and areal BMD measurement was significant (r = 0.68, p < 0.0001) with a 9.5% error; this improved significantly to 0.82 (7.2% error) when the BMD was divided by the vertebral depth from the radiograph. A real BMD showed a strong correlation with age (r = 0.82, p < 0.0001), wit...Continue Reading

References

Nov 1, 1986·The Journal of Bone and Joint Surgery. British Volume·A G VeldhuizenP J Webb
Mar 1, 1985·AJR. American Journal of Roentgenology·D J SartorisP Madvig
Jan 1, 1995·Bone·J E Compston
Mar 1, 1995·Calcified Tissue International·M A SabinI Fogelman

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Citations

Aug 15, 2000·Journal of Spinal Disorders·P J PapagelopoulosK N An
Sep 22, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S M OttL Newell-Morris
Apr 26, 2000·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·K MakiY Shibasaki
Oct 24, 2012·Journal of Osteoporosis·Sina GalloHope A Weiler
Jan 14, 2009·American Journal of Physical Anthropology·Sabrina C Agarwal, Marc D Grynpas
Sep 16, 2000·Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society·S M Shalet, R G Rosenfeld
Jul 1, 2000·Primates; Journal of Primatology·Shalini NairJeffrey Rogers
Apr 4, 2000·Physiological Reviews·K J Ellis
Apr 11, 2003·Primates; Journal of Primatology·Yasuhiro KikuchiYuzuru Hamada
Jul 28, 2021·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Eric SoGregory C Berlet

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