Evans syndrome and its link with systemic lupus erythematosus

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
Satish MendoncaM L Sharma

Abstract

Evans syndrome is a rare syndrome associated with the presence of autoimmune hemolytic anemia and simultaneous or sequential development of thrombocytopenia. It was first described by Evan and Duane in 1951. It is one of the rare presenting features of autoimmune disorders, especially systemic lupus erythematosus (SLE), and sometimes may even precede the onset of disease. Primary Evans syndrome with no cause is very rare and is seen in children. Here, we describe a case of secondary Evans syndrome with severe hemolytic anemia leading to acute kidney injury and recovery thereafter only to develop lupus nephritis a few months later. This is one of the rare presentations of SLE and there are only anecdotal case reports.

References

Jan 10, 2006·British Journal of Haematology·Alice Norton, Irene Roberts
Dec 6, 2008·Hematology·Kajal Kiran DhingraNaresh Gupta

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Citations

Nov 23, 2017·Case Reports in Pediatrics·Iván GonzálezLouis P Dehner

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