Event-related potential study of the effects of emotional facial expressions on task performance in euthymic bipolar patients

Applied Psychophysiology and Biofeedback
Estate M SokhadzeRif S El-Mallakh

Abstract

There appears to be a significant disconnect between symptomatic and functional recovery in bipolar disorder (BD). Some evidence points to interepisode cognitive dysfunction. We tested the hypothesis that some of this dysfunction was related to emotional reactivity in euthymic bipolar subjects may effect cognitive processing. A modification of emotional gender categorization oddball task was used. The target was gender (probability 25%) of faces with negative, positive, and neutral emotional expression. The experiment had 720 trials (3 blocks × 240 trials each). Each stimulus was presented for 150 ms, and the EEG/ERP responses were recorded for 1,000 ms. The inter-trial interval was varied in 1,100-1,500 ms range to avoid expectancy effects. Task took about 35 min to complete. There were 9 BD and 9 control subjects matched for age and gender. Reaction time (RT) was globally slower in BD subjects. The centro-parietal amplitudes at N170 and N200, and P200 and P300 were generally smaller in the BD group compared to controls. Latency was shorter to neutral and negative targets in BD. Frontal P200 amplitude was higher to emotional negative facial non-targets in BD subjects. The frontal N200 in response to positive facial emotion was...Continue Reading

References

Apr 1, 1979·The British Journal of Psychiatry : the Journal of Mental Science·S A Montgomery, M Asberg
Jul 1, 1978·Acta Psychologica·R NäätänenS Mäntysalo
Nov 1, 1978·The British Journal of Psychiatry : the Journal of Mental Science·R C YoungD A Meyer
Jun 1, 1992·Psychiatry Research·R C GurH C Kraemer
Jun 1, 1991·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·G L AhernM M Mesulam
Jan 1, 1995·Neuroscience and Biobehavioral Reviews·I Amado-BoccaraH Lôo
Jan 1, 1995·Journal of Psychiatric Research·S F Lewis, D L Garver
Aug 1, 1994·Biological Psychiatry·J M FordA Pfefferbaum
Apr 1, 1994·Biological Psychiatry·P J SantoshY N Mehra
May 1, 1993·Journal of Affective Disorders·B N GangadharC Umapathy
Jul 1, 1993·Psychophysiology·D FriedmanM Hamberger
Feb 28, 1997·Schizophrenia Research·J Addington, D Addington
Jul 1, 1997·The Journal of Neuropsychiatry and Clinical Neurosciences·H S Mayberg
Jan 22, 1998·Archives of General Psychiatry·F K Goodwin, S N Ghaemi
Jan 27, 1998·The Journal of Nervous and Mental Disease·S ParadisoR G Robinson
Mar 21, 1998·Psychophysiology·J Katayama, J Polich
May 8, 1998·Neuroscience Research·T F MünteS Johannes
Jul 29, 1998·Electroencephalography and Clinical Neurophysiology·G F PottsD M Tucker
Oct 21, 1998·Electroencephalography and Clinical Neurophysiology·F Bange, N Bathien
Nov 3, 1998·Biological Psychiatry·D UmbrichtJ Kane
Jan 23, 1999·Biological Psychiatry·D F SalisburyR W McCarley
Mar 17, 1999·Brain Research. Cognitive Brain Research·M StreitH W Müller-Gärtner
Jan 5, 2000·Psychological Medicine·F C MurphyE S Paykel
Jan 25, 2000·The British Journal of Psychiatry : the Journal of Mental Science·I N FerrierJ Scott
Mar 10, 2000·Journal of Affective Disorders·M P Caligiuri, J Ellwanger
Apr 8, 2000·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·J KayserF M Quitkin
May 29, 2000·Trends in Cognitive Sciences·J V HaxbyM I Gobbini
Oct 12, 2000·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·J Polich, K L Herbst
Nov 30, 2000·Biological Psychiatry·H P BlumbergD A Silbersweig
Mar 7, 2001·The British Journal of Psychiatry : the Journal of Mental Science·M P AustinG M Goodwin

❮ Previous
Next ❯

Citations

Oct 24, 2012·Cognitive Neuropsychiatry·Tamsyn E Van Rheenen, Susan L Rossell
Jun 20, 2013·Journal of Neuroengineering and Rehabilitation·Oonagh M GigginsBrian Caulfield
Jun 17, 2014·Neurophysiologie clinique = Clinical neurophysiology·D Delle-VigneS Campanella
Oct 13, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Daniel FeuerriegelHannah A D Keage
Nov 12, 2016·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Qin DaiZhengzhi Feng
Jan 10, 2014·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Adolfo BenitoJosé Manuel Montes
Dec 21, 2011·Neuroreport·Racheal Degabriele, Jim Lagopoulos
Jun 15, 2019·Journal of Affective Disorders·Masataka WadaYoshihiro Noda

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.