Event-related potentials indicate motivational relevance of cocaine cues in abstinent cocaine addicts

Psychopharmacology
Maria C van de LaarVincent M Hendriks

Abstract

Motivational drive and its underlying affect-related states are the core mechanisms that precede the seeking and taking of drugs in substance dependence. The present study aimed to investigate the motivational relevance of cocaine cues and whether or not an appetitive emotional system is involved employing event-related potential (ERP) measurements. Cocaine-addicted subjects and healthy controls were exposed to neutral and cocaine-related pictures whilst ERPs were recorded simultaneously over frontal, parietal and midline sites. Patients exhibited ERP amplitude discrepancies between neutral and cocaine-related pictures for N300, late slow positive wave (LSPW) and sustained slow positive wave (SSPW), whilst this effect was absent in control subjects. Differences in neutral and cocaine cue-evoked ERP waves were also found at left frontal sites for LSPW and SSPW in the patient group only. No group-specific cue-evoked ERP amplitudes were observed at parietal and midline sites. The findings confirm the assumption that cocaine cues induce motivational relevance in cocaine-dependent individuals. It is possible that exposure to cocaine cues triggers an appetitive emotional system since left frontal sites are assumed to be involved in p...Continue Reading

References

Sep 1, 1992·Brain and Cognition·R J Davidson
Nov 1, 1990·Brain and Cognition·S E Barrett, M D Rugg
Jan 1, 1989·Journal of Substance Abuse Treatment·V M HendriksP Geerlings
Jun 1, 1988·Journal of Personality and Social Psychology·D WatsonA Tellegen
Jan 1, 1987·British Journal of Addiction·L T Kozlowski, D A Wilkinson
Jul 1, 1986·Brain and Cognition·E K Silberman, H Weingartner
Apr 1, 1983·Electroencephalography and Clinical Neurophysiology·G GrattonE Donchin
Mar 1, 1994·Journal of Behavior Therapy and Experimental Psychiatry·M M Bradley, P J Lang
Sep 1, 1993·Brain Research. Brain Research Reviews·T E Robinson, K C Berridge
Dec 1, 1995·Child Development·N A FoxS Stewart
Apr 1, 1996·Current Opinion in Neurobiology·R A Wise
Oct 23, 1997·Neuron·H C BreiterS E Hyman
Jan 20, 1998·The American Journal of Psychiatry·L C MaasP F Renshaw
May 19, 1998·Journal of Psychopharmacology·A WeinsteinD J Nutt
Nov 20, 1998·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·P J LangB N Cuthbert
Jan 19, 1999·The American Journal of Psychiatry·A R ChildressC P O'Brien
Mar 31, 1999·Psychophysiology·W B McPherson, P J Holcomb
May 27, 1999·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·R VerheulP Geerlings
Sep 9, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·C A Warren, B E McDonough
Mar 24, 2000·Cerebral Cortex·E D LondonA Weinstein
Mar 31, 2000·Brain and Cognition·R J Davidson
Nov 4, 2000·The American Journal of Psychiatry·H GaravanE A Stein
Dec 5, 2000·Alcoholism, Clinical and Experimental Research·M J HerrmannA J Fallgatter
Jan 4, 2001·The American Journal of Psychiatry·B E WexlerJ C Gore
Feb 15, 2001·Addiction·T E Robinson, K C Berridge
Feb 24, 2001·Journal of Psychopharmacology·I H FrankenA Jansen
Nov 13, 2001·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·M J HerrmannA J Fallgatter
Mar 29, 2002·Brain Research. Cognitive Brain Research·W Caroline West, Phillip J Holcomb
Jul 12, 2002·Trends in Cognitive Sciences·John Kounios
Oct 3, 2002·The American Journal of Psychiatry·Rita Z Goldstein, Nora D Volkow
Nov 29, 2002·Cognitive, Affective & Behavioral Neuroscience·Robert West, Keisha Ross-Munroe
Apr 10, 2003·Journal of Cognitive Neuroscience·K R DaffnerP J Holcomb
Jun 6, 2003·Progress in Neuro-psychopharmacology & Biological Psychiatry·Ingmar H A Franken
Aug 5, 2003·Psychopharmacology·Ingmar H A FrankenWim van den Brink
Dec 8, 2004·Journal of Psychopharmacology·Ingmar H A FrankenWim van den Brink

❮ Previous
Next ❯

Citations

Aug 13, 2011·Psychopharmacology·Andrew J WatersIngmar H A Franken
Feb 6, 2007·Psychological Medicine·Dan I LubmanJ F William Deakin
Mar 12, 2008·Addiction Biology·Ingmar H A FrankenJan W Van Strien
Jun 19, 2009·Clinical EEG and Neuroscience·Natalie A CeballosRebecca J Houston
Nov 26, 2011·Reviews in the Neurosciences·Muhammad A ParvazRita Z Goldstein
May 27, 2015·The American Journal of Drug and Alcohol Abuse·Marien LievaartIngmar H A Franken
May 23, 2012·Neuroscience and Biobehavioral Reviews·Marianne LittelIngmar H A Franken
Sep 8, 2009·Biological Psychology·Eddie Harmon-JonesCarly K Peterson
Oct 22, 2008·Eating Behaviors·Ilse M T NijsPeter Muris
Mar 13, 2008·The European Journal of Neuroscience·Klaus WölflingSabine M Grüsser
Apr 1, 2011·The European Journal of Neuroscience·Jonathan P DunningRita Z Goldstein
Jun 10, 2014·Developmental Science·Anirudh SreekrishnanMichael J Crowley
Nov 1, 2005·European Journal of Pharmacology·Ingmar H A FrankenWim van den Brink
Jun 9, 2015·Physiology & Behavior·Jiang HaifengZhao Min
Apr 21, 2016·Psychophysiology·Nicole MechinJoshua A Hicks
Jul 24, 2013·Neuroscience and Biobehavioral Reviews·Desirée B SpronkRobbert J Verkes
Apr 30, 2014·The International Journal of Neuropsychopharmacology·Catarine Lima ContiEster Miyuki Nakamura-Palacios
May 6, 2014·Social Cognitive and Affective Neuroscience·Anna WeinbergChristopher J Patrick
Jun 7, 2014·Frontiers in Behavioral Neuroscience·Rinaldo L PerriFrancesco Di Russo
Sep 11, 2016·Journal of Psychiatric Research·Janine Andrade MosconEster Miyuki Nakamura-Palacios
Aug 19, 2010·Journal of Psychopharmacology·Marianne Littel, Ingmar H A Franken
Oct 10, 2013·Clinical EEG and Neuroscience·Salvatore CampanellaNash Boutros
Jan 1, 2013·Socioaffective Neuroscience & Psychology·Vaughn R SteeleNicole Prause
Sep 21, 2017·Psychological Science·Kevin H RobertsRebecca M Todd
Feb 25, 2020·Health Communication·Tae-Joon MoonDonald M Dougherty
Mar 23, 2017·Frontiers in Behavioral Neuroscience·Alejandro OrricoTeodoro Zornoza
Jun 3, 2021·Proceedings of the National Academy of Sciences of the United States of America·Muhammad A ParvazRita Z Goldstein
Oct 24, 2021·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Yi ZhangJunfeng Sun

❮ Previous
Next ❯

Related Concepts

Related Feeds

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.

© 2022 Meta ULC. All rights reserved