Everolimus drug-eluting stent performance in patients with long coronary lesions: The multicenter Longprime registry

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
José Francisco Díaz FernándezFranck Albert

Abstract

To assess the efficacy and safety of the Xience Prime everolimus-eluting stent (EES) in long coronary lesions in a real-world population. Long lesions are considered difficult technically and in terms of achieving successful clinical outcomes. With first generation DES, MACE can be as high as 10% at a short-medium term follow-up. There are a few data available in this subset regarding the use of second generation DES METHODS: A prospective, multicenter registry of consecutive patients (aged 64.8 ± 11.2 years, 77% men and 33% diabetics) in 29 tertiary hospitals with de novo > 24 mm lesions in vessels of 2.25-4 mm was performed. The primary and secondary endpoints were major adverse cardiac events (MACE; cardiac death, myocardial infarction, and target lesion revascularization) and stent thrombosis (ST) at 1, 12, and 24 months. Patients were on dual antiplatelet therapy during 12 months. A total of 610 patients with 705 long lesions were included (1.2 per patient). Lesion length was 34.59 ± 11.17 mm and vessel size 2.93 ± 0.41 mm. Stented length was 39.83 ± 14.08 mm (1.4 stents per lesion). Predilatation/postdiltatation was performed in 75 and 33% of the cases, intravascular ultrasound in 15%. The device success rate was 99.1%. M...Continue Reading

References

Jan 10, 2006·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Young-Hak KimSeung-Jung Park
Oct 25, 2006·Circulation·Young-Hak KimUNKNOWN Long-DES-II Study Investigators
Feb 14, 2007·The New England Journal of Medicine·Adnan KastratiAlbert Schömig
Feb 14, 2007·The New England Journal of Medicine·Gregg W StoneMartin B Leon
Aug 28, 2012·Circulation·Kristian ThygesenShanti Mendis
Aug 21, 2013·The American Journal of Cardiology·Michael LeeUNKNOWN RESOLUTE US and RESOLUTE Asia Investigators
Feb 16, 2015·Archives of Cardiovascular Diseases·Aurélie ManchuelleGilles Lemesle
Apr 9, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Alfonso IelasiAzeem Latib

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Citations

Mar 22, 2019·Minerva cardioangiologica·Lorenzo GenuardiCarlo Trani

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