Evidence-based analysis of peripheral arterial disease screening based on the WHO criteria

International Angiology : a Journal of the International Union of Angiology
Sohan ShahFrancesco Torella

Abstract

Peripheral arterial disease (PAD) is an increasingly prevalent condition caused by atherosclerosis of the lower limb arteries. The majority of patients with PAD also have atherosclerosis of the coronary and cerebral vessels, therefore screening for PAD may detect patients at risk of myocardial infarction and/or stroke, but the clinical benefit of mass screening for PAD is uncertain. Using the ten WHO criteria for evaluation of a screening program, we analyzed the potential merits of conducting PAD screening, using ABPI, by reviewing the evidence within the domain of each individual criterion. A comprehensive literature search was systematically carried out in order to identify relevant articles in relation to PAD screening. An evaluation and critical overview of all evidence in favor of and against the implementation of PAD screening was undertaken. Screening for PAD fits most of the WHO criteria. On current evidence, and generally in line with current guidelines, a potential target population could include anybody aged 70 years or older and those aged 45-69 with at least one risk factor for PAD. However, evidence on the cost-effectiveness of screening is based purely on theoretical modelling. Furthermore, the benefits of some ...Continue Reading

Citations

Feb 14, 2020·International Angiology : a Journal of the International Union of Angiology·Bin XuLi-Ge Liu
Apr 17, 2020·International Angiology : a Journal of the International Union of Angiology·Konstantinos MpatzalexisAthanasios D Giannoukas

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