Evidence-based guidelines for the pharmacological treatment of schizophrenia: Updated recommendations from the British Association for Psychopharmacology

Journal of Psychopharmacology
Thomas R E BarnesAlison R Yung

Abstract

These updated guidelines from the British Association for Psychopharmacology replace the original version published in 2011. They address the scope and targets of pharmacological treatment for schizophrenia. A consensus meeting was held in 2017, involving experts in schizophrenia and its treatment. They were asked to review key areas and consider the strength of the evidence on the risk-benefit balance of pharmacological interventions and the clinical implications, with an emphasis on meta-analyses, systematic reviews and randomised controlled trials where available, plus updates on current clinical practice. The guidelines cover the pharmacological management and treatment of schizophrenia across the various stages of the illness, including first-episode, relapse prevention, and illness that has proved refractory to standard treatment. It is hoped that the practice recommendations presented will support clinical decision making for practitioners, serve as a source of information for patients and carers, and inform quality improvement.

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Sep 17, 2013·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Philip D HarveyAntony Loebel
Oct 4, 2013·JAMA Psychiatry·Roman KotovEvelyn J Bromet
Oct 5, 2013·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Cecilia BrainMargda Waern
Oct 8, 2013·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·John M KaneChristoph U Correll
Oct 8, 2013·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Davy VancampfortMarc De Hert
Oct 24, 2013·Annals of General Psychiatry·José M OlivaresAndreas Schreiner
Nov 20, 2013·Neuroscience and Biobehavioral Reviews·Keith A FeigensonSteven M Silverstein
Nov 20, 2013·Annals of Internal Medicine·Karl RichardsonEmil M deGoma
Nov 22, 2013·The Annals of Pharmacotherapy·Kylee A Funk, Jolene R Bostwick
Nov 23, 2013·Parkinsonism & Related Disorders·Pierre R Burkhard
Dec 18, 2013·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Elena Huerta-RamosJudith Usall
Dec 24, 2013·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Cecilia BrainMargda Waern
Jan 22, 2014·BJOG : an International Journal of Obstetrics and Gynaecology·Simone N VigodJoel Ray
Feb 4, 2014·Schizophrenia Research·Christopher K CainDonald C Goff
Feb 20, 2014·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Daniel UmbrichtLuca Santarelli
Feb 28, 2014·CNS Spectrums·Leslie Citrome, Jan Volavka
Mar 5, 2014·Circulation. Arrhythmia and Electrophysiology·Marieke T BlomHanno L Tan
Apr 10, 2014·Evidence-based Mental Health·Markus Dold, Stefan Leucht
Apr 15, 2014·Psychiatry Research·Rachel UpthegroveLisa Jones
May 13, 2014·Lancet·Seena FazelPaul Lichtenstein
May 23, 2014·JAMA : the Journal of the American Medical Association·Joseph P McEvoyT Scott Stroup
May 28, 2014·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Tiago Reis MarquesShitij Kapur
Jun 28, 2014·Neuropsychiatric Disease and Treatment·Lulu Zhang, Jingping Zhao
Jul 26, 2014·Patient Related Outcome Measures·Peter M HaddadJan Scott
Jul 27, 2014·Journal of the American Academy of Child and Adolescent Psychiatry·D R MiklowitzTyrone D Cannon
Jul 30, 2014·Psychological Medicine·Craig MorganPaola Dazzan
Oct 18, 2014·The British Journal of Psychiatry : the Journal of Mental Science·Mike CrawfordDavid Shiers
Nov 5, 2014·Southern Medical Journal·Tapan ParikhSteven Lippmann
Nov 11, 2014·Journal of Multidisciplinary Healthcare·Matisyahu ShulmanAleksey Tentler
Nov 26, 2014·Schizophrenia Bulletin·Minna TorniainenJari Tiihonen
Dec 3, 2014·Nature Reviews. Endocrinology·Richard I G Holt, A J Mitchell
Dec 19, 2014·The Australian and New Zealand Journal of Psychiatry·Grant E SaraWayne D Hall
Dec 24, 2014·Schizophrenia Bulletin·Marc-Antoine d'Albis, Josselin Houenou
Dec 24, 2014·Basic & Clinical Pharmacology & Toxicology·Zandra Nymand Ennis, Per Damkier
Jan 27, 2015·JAMA Internal Medicine·Shelly L GrayEric B Larson
Mar 3, 2015·The American Journal of Psychiatry·Ashleigh LinAlison R Yung
Mar 15, 2015·BMJ : British Medical Journal·Kyla H ThomasDavid Gunnell
Mar 25, 2015·Movement Disorders : Official Journal of the Movement Disorder Society·Roberto ErroMichele Tinazzi
Apr 23, 2015·Schizophrenia Research·Suraj S MothiMatcheri S Keshavan
Apr 29, 2015·Schizophrenia Research·Sophie M HeringaI E C Sommer
May 7, 2015·Schizophrenia Bulletin·Randal G Ross, Robert Freedman
May 20, 2015·Molecular Psychiatry·Thomas W WeickertCynthia Shannon Weickert
May 26, 2015·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Pál CzoborJan Volavka
May 28, 2015·The International Journal of Neuropsychopharmacology·Xinyu ZhouPeng Xie
Jun 3, 2015·JAMA : the Journal of the American Medical Association·Krista F HuybrechtsSonia Hernández-Díaz
Jun 4, 2015·The Journal of Neuropsychiatry and Clinical Neurosciences·Jeff VictoroffSamuel Shillcutt
Jun 6, 2015·The British Journal of Psychiatry : the Journal of Mental Science·Lucia R ValmaggiaPhilip McGuire
Jun 13, 2015·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Neal R SwerdlowGregory A Light
Jun 20, 2015·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Richard S E KeefeDana C Hilt
Aug 11, 2015·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Benjamin SneiderJimmi Nielsen
Aug 12, 2015·Social Psychiatry and Psychiatric Epidemiology·Nanna Gilliam ToftdahlC Hjorthøj
Aug 12, 2015·Nature Communications·G P AmmingerP D McGorry
Aug 15, 2015·Clinical Pharmacology and Therapeutics·Francesco SalvoInvestigators of the ARITMO Consortium
Sep 1, 2015·Schizophrenia Research·Lawrence H YangCheryl M Corcoran
Sep 4, 2015·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·R Douglas WilsonMichiel Van den Hof
Sep 29, 2015·Current Neuropharmacology·Lurdes TseFidel Vila-Rodriguez
Oct 2, 2015·World Journal of Psychiatry·Antonio TundoLuca Proietti
Oct 4, 2015·Schizophrenia Research·Andreas SchreinerLudger Hargarter
Oct 18, 2015·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Rosa Ayesa-ArriolaBenedicto Crespo-Facorro
Nov 3, 2015·International Journal of Clinical Pharmacology and Therapeutics·Cai-Lan HouYu-Tao Xiang
Nov 14, 2015·Schizophrenia Bulletin·Sonia DollfusRémy Morello
Dec 10, 2015·The Journal of Clinical Psychiatry·Nicholas MeyerJames MacCabe
Dec 10, 2015·The Journal of Clinical Psychiatry·Frederik VandenbergheChin B Eap
Dec 15, 2015·Neurology and Therapy·William M Greenberg, Leslie Citrome
Jan 23, 2016·Neuropsychiatric Disease and Treatment·Craig KarsonSteve J Offord
Feb 3, 2016·International Journal of Mental Health Nursing·Adam SearbyIan McGrath
Feb 9, 2016·Obstetrics and Gynecology·Gillian E HanleySteven G Morgan