PMID: 16639989Apr 28, 2006Paper

Evidence-based medicine in pathology: an introduction

Seminars in Diagnostic Pathology
Alberto M Marchevsky

Abstract

Evidence-based medicine (EBM) is a school of thought that has spread rapidly through medicine in the past 2 decades and is eliciting an increasing interest in Anatomic Pathology and Laboratory Medicine. It has been defined as "the conscientious, explicit, and judicious use of current best evidence in making decisions about the care of individual patients." The environmental factors that created a need for EBM and basic concepts of this discipline are reviewed. Methods for the accrual and critical appraisal of the validity of available evidence and its impact, applicability and usefulness in pathology practice are discussed. Basic concepts of bayesian data analysis with an emphasis on concepts such as prior and posterior probability and the use of "holdout" or "test" data are introduced. The future of EBM in pathology is discussed and potential applications of these concepts to pathology practice and research are proposed.

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Citations

Oct 29, 2011·Archives of Pathology & Laboratory Medicine·Mark R Wick, Alberto M Marchevsky
Jun 3, 2008·Hematology/oncology Clinics of North America·Alberto M MarchevskyRuta Gupta
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Oct 31, 2014·Archives of Pathology & Laboratory Medicine·Alberto M Marchevsky, Mark R Wick
Jul 27, 2007·International Journal of Surgical Pathology·Jose Costa
Dec 20, 2008·American Journal of Clinical Pathology·Jonathon HerbstAlberto Marchevsky
Feb 24, 2007·Laboratory Investigation; a Journal of Technical Methods and Pathology·James M Crawford

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