Evidence-based recommendations for energy intake in pregnant women with obesity.

The Journal of Clinical Investigation
Jasper MostLeanne M Redman

Abstract

In women with obesity, excess gestational weight gain (≥270 g/week) occurs in two out of three pregnancies and contributes to metabolic impairments in both mother and baby. To improve obstetrical care, objectively assessed information on energy balance is urgently needed. The objective of this study was to characterize determinants of gestational weight gain in women with obesity. This was a prospective, observational study of pregnant women with obesity. The primary outcome was energy intake calculated by the energy intake-balance method. Energy expenditure was measured by doubly-labeled water and whole-room indirect calorimetry and body composition as 3-compartment model by air displacement plethysmography and isotope dilution in early (13-16 weeks) and late pregnancy (35-37 weeks). In pregnant women with obesity (n=54), recommended weight gain (n=8, 15%) during the second and third trimesters was achieved when energy intake was 125±52 kcal/d less than energy expenditure. In contrast, women with excess weight gain (67%) consumed 186±29 kcal/d more than they expended (P<0.001). Energy balance affected maternal adiposity (recommended: -2.5±0.8 kg fat mass, excess: +2.2±0.5, inadequate: -4.5±0.5, P<0.001), but not fetal growth. ...Continue Reading

Associated Clinical Trials

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Citations

Sep 24, 2019·The Journal of Clinical Investigation·Sarah S Comstock
Jan 1, 2020·Obesity·Jasper MostLeanne M Redman
Jan 7, 2020·The Journal of Clinical Endocrinology and Metabolism·Jasper MostLeanne M Redman
Sep 26, 2020·Nutrition Reviews·Claudia SavardAnne-Sophie Morisset
Jul 8, 2020·International Journal of Environmental Research and Public Health·Lucy PeacockAngela C Flynn
Aug 9, 2019·Nutrients·Jasper MostLeanne M Redman
Nov 27, 2020·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Sara ParrettiniElisabetta Torlone
Feb 8, 2020·Eating Behaviors·Xuyang TangRebecca A Krukowski

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Clinical Trials Mentioned

NCT01954342

Software Mentioned

SAS
BODPOD
Moms
COSMED
DALI
LIMIT
LIFE
RADIEL
SmartIntake
UPBEAT

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