PMID: 8583617Mar 1, 1996Paper

Evidence for a mechanistic association between nonbacterial prostatitis and levels of urate and creatinine in expressed prostatic secretion

The Journal of Urology
B E Persson, G Ronquist

Abstract

Chronic prostatitis is a common disease of the late teenage years, which affects patients for many years. In the majority of cases etiology is unknown but in some cases prostatitis is clearly caused by microorganisms that result from overuse of antibiotic drugs. We attempt to gain further knowledge about the etiology of the disease. We studied 56 patients with nonbacterial prostatitis in regard to whether urine reflux into the prostatic ducts was responsible for increased concentrations of creatinine, urate and white blood cells in expressed prostatic secretion. The patients were interviewed using a standard questionnaire. A relationship was demonstrated between pain estimated in accordance with a scoring scale, and expressed prostatic secretion contents of white blood cells, urate and creatinine. These results provide further support of the role of reflux into the prostatic ducts as an underlying mechanism initiating a chemical inflammatory reaction. Urate appears to be the chemical agent eliciting this inflammatory response.

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Citations

May 15, 1998·The Prostate·B O NilssonG Ronquist
Nov 28, 2001·Current Infectious Disease Reports·Granville L. Lloyd, Anthony J. Schaeffer
Jun 27, 2002·Current Urology Reports·R O Roberts, S J Jacobsen
Jun 27, 2002·Current Urology Reports·D Caropreso, T D Moon
Jun 27, 2002·Current Urology Reports·J M Potts, E O'Dougherty
Aug 1, 2002·Current Urology Reports·Jeannette M Potts
Jul 29, 2003·Current Urology Reports·Caroline Maake, Hubert John
Dec 20, 1999·Seminars in Roentgenology·S R Potter, A W Partin
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Jan 1, 2008·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Ram Vaidyanathan, Vibhash C Mishra
Jun 11, 2009·International Journal of Andrology·B FibbiM Maggi
Dec 10, 1999·The Urologic Clinics of North America·J C Nickel
Sep 14, 1996·Lancet·B E Persson, G Ronquist
Jun 25, 2013·Cellular & Molecular Biology Letters·Sudhakar Veeranki
Aug 12, 2010·FEMS Immunology and Medical Microbiology·Sławomir LetkiewiczAndrzej Górski
Sep 30, 2016·The Prostate·Yasuhito FunahashiMomokazu Gotoh
Feb 15, 2000·BJU International·J C Nickel
Feb 28, 2006·Fertility and Sterility·Ruben Dario MotrichVirginia Elena Rivero
May 3, 2006·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Amir M ZiaeeMojgan Karbakhsh
Mar 21, 1998·The Journal of Urology·M M CollinsM J Barry
Apr 25, 2008·Scandinavian Journal of Urology and Nephrology·Hans Hedelin, Magnus Fall
Aug 30, 2014·Urology·Adel KurkarAhmed Altaher
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Oct 13, 2006·Current Opinion in Urology·W Weidner, M Ludwig
Mar 2, 2012·Korean journal of urology·Kyung Seop Lee, Jae Duck Choi
Dec 24, 2002·Prostate Cancer and Prostatic Diseases·H S Gurunadha Rao Tunuguntla, C P Evans
Jul 30, 2014·Bulletin of Experimental Biology and Medicine·G A LapiiA I Neimark

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