Evidence for a Supraspinal Contribution to the Human Crossed Reflex Response During Human Walking

Frontiers in Human Neuroscience
Natalie Mrachacz-KerstingVéronique Marchand-Pauvert

Abstract

In humans, an ipsilateral tibial nerve (iTN) stimulation elicits short-latency-crossed-responses (SLCR) comprised of two bursts in the contralateral gastrocnemius lateralis (cGL) muscle. The average onset latency has been reported to be 57-69 ms with a duration of 30.4 ± 6.6 ms. The aim of this study was to elucidate if a transcortical pathway contributes to the SLCR. In Experiment 1 (n = 9), single pulse supra-threshold transcranial magnetic stimulation (supraTMS) was applied alone or in combination with iTN stimulation (85% of the maximum M-wave) while participants walked on a treadmill (delay between the SLCR and the motor evoked potentials (MEP) varied between -30 and 200 ms). In Experiment 2 (n = 6), single pulse sub-threshold TMS (subTMS) was performed and the interstimulus interval (ISI) varied between 0-30 ms. In Experiment 3, somatosensory evoked potentials (SEPs) were recorded during the iTN stimulation to quantify the latency of the resulting afferent volley at the cortical level. SLCRs and MEPs in cGL occurred at 63 ± 6 ms and 29 ± 2 ms, respectively. The mean SEP latency was 30 ± 3 ms. Thus, a transcortical pathway could contribute no earlier than 62-69 ms (SEP+MEP+central-processing-delay) after iTN stimulation. C...Continue Reading

References

Aug 1, 1987·The Journal of Physiology·H HultbornE Pierrot-Deseilligny
Jan 1, 1981·Experimental Brain Research·E Pierrot-DeseillignyC Morin
Jun 1, 1997·Experimental Brain Research·M SchubertV Dietz
Jan 1, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·K Kurusu, J Kitamura
Feb 19, 2003·Brain Research. Brain Research Reviews·Simon J B ButtOle Kiehn
Jun 22, 1957·Nature·R M ECCLES, A LUNDBERG
Oct 22, 2005·Experimental Brain Research·N Mrachacz-KerstingT Sinkjaer
Sep 22, 2007·Brain Research Reviews·Elzbieta Jankowska
May 30, 2008·Journal of Neurophysiology·Zoltán BiróSten Grillner
Oct 9, 2009·Journal of Neurophysiology·Peter W Stubbs, Natalie Mrachacz-Kersting
Nov 26, 2010·Journal of Neurophysiology·Peter W StubbsNatalie Mrachacz-Kersting
Aug 16, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·P W StubbsN Mrachacz-Kersting
Jan 23, 2013·The Journal of Physiology·Elzbieta Jankowska, Ingela Hammar
Feb 22, 2013·Journal of Neurophysiology·Sabata GervasioNatalie Mrachacz-Kersting
Aug 7, 2013·The Journal of Physiology·Andrew J T StevensonNatalie Mrachacz-Kersting
Feb 7, 2014·Journal of Neurophysiology·Berthe Hanna-BoutrosVéronique Marchand-Pauvert
Jun 13, 2015·Journal of Neurophysiology·Sabata GervasioNatalie Mrachacz-Kersting

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Citations

Aug 23, 2018·European Journal of Applied Physiology·Sabata GervasioNatalie Mrachacz-Kersting
Nov 7, 2019·Journal of Neurophysiology·David J Maxwell, Demetris S Soteropoulos

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