PMID: 6108033Oct 1, 1980Paper

Evidence for alpha-adrenergic receptors mediated TSH release in men

Acta Endocrinologica
S Zgliczyński, M Kaniewski

Abstract

In order to elucidate the role of the adrenergic nervous system in the mechanism of TSH release in men the effects of alpha- and beta-receptors blocking agents were studied in 11 healthy volunteers. Phentolamine administered iv as a bolus injection in a dose of 10 mg, significantly lowered the TSH release in basal condition and in response to TRH stimulation. However, propranolol in a dose of 0.1 mg/kg administered in the same fashion as phentolamine had no effect on the TSH secretion. The results obtained suggest that the alpha-receptors of the adrenergic system are involved in the physiological mechanism which stimulates TSH release in men.

Citations

Jan 1, 1989·Pharmacology & Therapeutics·M J Fregly
Nov 28, 2012·European Journal of Endocrinology·Amnon ZungShlomo Almashanu
Apr 1, 1996·The International Journal of Biochemistry & Cell Biology·P CabartD Jandová
Sep 1, 1999·Clinical Endocrinology·E LeeL A Burmeister
Jan 1, 1988·Chronobiology International·J SalvadorM F Scanlon
Oct 1, 1993·Journal of Endocrinological Investigation·R Toni, R M Lechan

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