PMID: 9535123Apr 16, 1998Paper

Evidence for an inhibition by endogenous galanin of neurogenic cutaneous vasodilatation in the pigeon

Neuroscience Letters
Péter SánthaG Jancsó

Abstract

The effect of high affinity galanin antagonist M35 on neurogenic cutaneous vasodilatation has been studied in the pigeon using a Laser Doppler Imager. Cutaneous application of mustard oil or antidromic electrical stimulation of a cutaneous nerve produced a small increase in skin blood flow. Close arterial injection of M35 prior to chemical or electrical stimulation resulted in a marked augmentation of the vasodilatory response. This effect was abolished by chronic denervation. The results suggest a nerve-mediated inhibitory effect of endogenous galanin on neurogenic cutaneous vasodilatation in the pigeon skin and provide the first experimental evidence for an inhibitory local regulatory function of cutaneous sensory nerves at least in the avian skin.

References

Aug 1, 1985·Brain Research Bulletin·G Skofitsch, D M Jacobowitz
May 1, 1993·Agents and Actions·G JancsóH Sann

❮ Previous
Next ❯

Citations

May 3, 2000·The European Journal of Neuroscience·B HeppelmannM Pawlak
Apr 23, 2004·The Journal of Investigative Dermatology·Barbara KoflerJohann W Bauer
Jun 22, 2006·Journal of the Peripheral Nervous System : JPNS·Attila DallosSándor Husz
Oct 19, 2013·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Jérémy ChéretChristelle Le Gall-Ianotto
Jun 27, 2020·International Journal of Molecular Sciences·Tamara SzabadosPéter Bencsik

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.