Evidence for direct reciprocal interactions between the central rhythm generators for spinal "respiratory" and locomotor activities in the rabbit

Experimental Brain Research
D Viala

Abstract

Rhythm generators for locomotion and respiration have been previously identified in the high spinal rabbit treated with nialamide and DOPA. In curarized preparations, with no sensory feedback, simultaneous recordings of motor commands from the nerves to the diaphragm and to several hindlimb nerves have demonstrated that central (intraspinal) interactions exist between these respiratory and locomotor activities. The purpose of the present study was to investigate the nature of these interactions. Two main possibilities existed: "direct" interactions taking place between the rhythm generators; the activity of one of the rhythm generators modifying the other generator's activity at its "output" (at the interneuronal or motoneuronal level). The present analysis of the timing (and resetting) of activities in the phrenic, hindlimb extensor (gastrocnemius medialis) and flexor (tibialis anterior) nerves suggests a strong direct interaction between the two sets of rhythm generators. Each new locomotor cycle thus only begins at the termination of a "long-lasting phrenic burst" and a respiratory burst can only occur at certain parts of a locomotor cycle.

Citations

Jan 1, 1990·Neurosurgical Review·E D Schomburg
Apr 1, 1996·Respiration Physiology·M A ReinosoR D Hubmayr
Feb 1, 1990·Neuroscience Research·E D Schomburg
Nov 1, 1988·Neuroscience·E Garcia-Rill, R D Skinner
Dec 1, 1996·Respiration Physiology·B Rassler, J Kohl
Nov 25, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·B RasslerH Scholle
Oct 20, 2001·Journal of Experimental Psychology. Human Perception and Performance·P G AmazeenP J Beek
Mar 1, 1996·Journal of Motor Behavior·B. RasslerR. Junghans
Mar 1, 2008·Clinical and Experimental Pharmacology & Physiology·Ann K GoodchildPaul M Pilowsky
Oct 1, 1987·Acta Physiologica Scandinavica·E Hohtola, K Johansen
Oct 24, 1998·Clinical Physiology·J Rittweger, A Pöpel
Jun 15, 2010·Respiratory Physiology & Neurobiology·Erika IwamotoTsutomu Inamizu
Aug 25, 2009·Respiratory Physiology & Neurobiology·Michael A LanePaul J Reier
Dec 2, 2006·Neuroscience·J GravelR Dubuc
Oct 10, 2006·Brain Research Bulletin·T W Ford, P A Kirkwood
Jan 22, 2010·International Journal of Stroke : Official Journal of the International Stroke Society·O WalusinskiJ Bogousslavsky
Oct 26, 2007·Journal of Dental Research·H KoizumiM Kogo
Oct 17, 2008·The Journal of Comparative Neurology·Michael A LanePaul J Reier
Apr 9, 2020·Brain Sciences·Ross Howard Sanders, Daniel J Levitin
Feb 6, 2020·Frontiers in Systems Neuroscience·Victoria N JensenSteven A Crone
Aug 5, 2015·Journal of Neurotrauma·Michael George Zaki Ghali, Vitaliy Marchenko
Apr 12, 2019·Frontiers in Neuroscience·Natalia A ShevtsovaTatiana Bezdudnaya
Apr 5, 2020·Neural Regeneration Research·George Zaki GhaliEmil Zaki Ghali
Dec 22, 1990·The Journal of Comparative Neurology·H H EllenbergerH G Goshgarian
Mar 31, 2005·Revue neurologique·O WalusinskiJ-P Neau

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