Evidence for force-feedback inhibition in chronic stroke

IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society
Joseph M Hidler, B D Schmit

Abstract

The presence of force-feedback inhibition was explored during reflex responses in five subjects with known incidence of stroke. Using constant velocity stretches, it was previously found that after movement onset, active reflex force progressively increases with increasing joint angle, at a rate proportional to a fractional exponent of the speed of stretch. However, after the reflex force magnitude exceeds a particular level, it begins rolling off until maintaining a steady-state value. The magnitudes of these force plateaus are correlated with the speed of stretch, such that higher movement speeds result in higher steady-state forces. Based upon these previous studies, we hypothesized that force plateau behavior could be explained by a force-feedback inhibitory pathway. To help facilitate an understanding of this stretch reflex force roll off, a simple model representing the elbow reflex pathways was developed. This model contained two separate feedback pathways, one representing the monosynaptic stretch reflex originating from muscle spindle excitation, and another representing force-feedback inhibition arising from force sensitive receptors. It was found that force-feedback inhibition altered the stretch reflex response, res...Continue Reading

References

Jan 1, 1979·Annual Review of Physiology·J C Houk
Sep 1, 1979·Experimental Brain Research·W Z RymerP E Crago
Jan 1, 1992·Experimental Brain Research·V DietzM Trippel
Dec 1, 1989·The Journal of Physiology·J J JackR C Roberts
Dec 1, 1989·The Journal of Physiology·J F IlesR C Roberts
Dec 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·P J Delwaide, E Oliver
Apr 1, 1970·Journal of Neurology, Neurosurgery, and Psychiatry·D BurkeJ W Lance
Dec 1, 1971·Journal of Neurology, Neurosurgery, and Psychiatry·P Ashby, D Burke
Aug 1, 1981·Journal of Neurology, Neurosurgery, and Psychiatry·A Tang, W Z Rymer
Jan 1, 1981·Journal of Biomechanics·K N AnE Y Chao
Sep 1, 1995·Journal of Neurology, Neurosurgery, and Psychiatry·J D GivenW Z Rymer
May 1, 1995·Journal of Biomechanics·W M MurrayT S Buchanan
Jan 1, 1994·Experimental Brain Research·J P GossardH Hultborn
Dec 1, 1995·Progress in Neurobiology·R B Stein
Mar 1, 1996·Journal of Biomechanics·G J LorenR L Lieber
Apr 4, 1998·The Journal of Physiology·A Prochazka, M Gorassini
Jun 18, 1999·The Journal of Hand Surgery : Journal of the British Society for Surgery of the Hand·B O LjungJ Fridén
Sep 25, 1999·IEEE Transactions on Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·J M Hidler, W Z Rymer
Nov 5, 1999·Brain : a Journal of Neurology·L R WilsonD Burke
Jun 1, 2000·Journal of Biomechanics·W M MurrayS L Delp
Dec 28, 2000·IEEE Transactions on Bio-medical Engineering·J M Hidler, W Z Rymer
Jan 26, 2002·Experimental Brain Research·M M MirbagheriR E Kearney
Feb 21, 2002·Annals of Biomedical Engineering·D G KamperW Z Rymer
Jun 19, 2002·Experimental Brain Research·Brian D SchmitW Zev Rymer
Aug 14, 2002·IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society·Vivian K MushahwarArthur Prochazka
May 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·G RUSHWORTH

❮ Previous
Next ❯

Citations

Jul 14, 2007·Muscle & Nerve·Samir G SanganiBrian D Schmit
May 9, 2008·IEEE Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society·Sue Ann SistoPouran D Faghri
Feb 9, 2018·Journal of Applied Physiology·Allison S HyngstromMatthew J Durand
Nov 1, 2018·Journal of Neurophysiology·Spencer A MurphyAllison Hyngstrom
Aug 2, 2019·Disability and Rehabilitation. Assistive Technology·Lorenzo GaravagliaSimone Pittaccio

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology
Hong-You GeOle Kaeseler Andersen
The Journal of Orthopaedic and Sports Physical Therapy
M MorelliS J Sullivan
Archives of Physical Medicine and Rehabilitation
M MorelliS J Sullivan
© 2022 Meta ULC. All rights reserved