Evidence for the disproportionate mapping of olfactory airspace onto the main olfactory bulb of the hamster

The Journal of Comparative Neurology
T A Schoenfeld, Thomas K Knott

Abstract

Olfactory receptor neurons (ORNs) project to the rodent main olfactory bulb (MOB) from spatially distinct air channels in the olfactory recesses of the nose. The relatively smooth central channels of the dorsal meatus map onto the dorsal MOB, whereas the highly convoluted peripheral channels of the ethmoid turbinates project to the ventral MOB. Medial and lateral components of each projection stream innervate the medial and lateral MOB, respectively. To ascertain whether such topography entails the disproportionate representation seen in other sensory maps, we used disector-based stereological techniques in hamsters to estimate the number of ORNs associated with each channel in the nose and the number of their targets (glomeruli and mitral and tufted cells) in corresponding divisions of the MOB. Each circumferential half of the MOB (dorsal/ventral, medial/lateral) contained about 50% of the 3,100 glomeruli and about 50% of the 160,000 mitral and tufted cells per bulb. We found equivalent numbers of ORNs with dendritic knobs in the medial and lateral channels (4.5 million each). However, the central channels had only 2 million knobbed ORNs, whereas the peripheral channels had 7 million. Thus, there is a disproportionate mapping ...Continue Reading

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Citations

Nov 13, 2008·Cognitive Neurodynamics·Daniel Rojas-Líbano, Leslie M Kay
Jan 16, 2007·Chemical Senses·Geoffrey C YangMaxwell M Mozell
Jan 23, 2009·Anatomical Science International·Shinji Matsutani, Noboru Yamamoto
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Sep 14, 2011·PloS One·Josif StakicEdwin R Griff
Apr 27, 2010·PLoS Pathogens·Richard A BessenJames A Wiley
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Jul 9, 2020·The Journal of Comparative Neurology·Lutz Slomianka
Jul 14, 2021·Physiological Reviews·Ivan ManziniCorrado Di Natale

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