PMID: 11309142Apr 20, 2001Paper

Evidence for the plant-specific intercellular transport of the Arabidopsis copper chaperone CCH

The Plant Journal : for Cell and Molecular Biology
Helena MiraLola Peñarrubia

Abstract

Arabidopsis copper chaperone (CCH) belongs to a family of eukaryotic proteins that participates in intracellular copper homeostasis by delivering this metal to the secretory pathway. In this work we show that the CCH protein is mainly located along the vascular bundles of senescing leaves and petioles, as shown by tissue prints and immunohistochemical detection. CCH protein also accumulates in stem sieve elements and is collected in phloem exudates. Accordingly, Arabidopsis CCH is the only member of the metallochaperone family described to function intercellularly to date. Moreover, the CCH protein remains stable when plants are subjected to excess copper that causes a rapid and specific decrease in its mRNA. These facts point to a role for CCH in copper mobilization from decaying organs towards reproductive structures, as a result of metalloprotein breakdown.

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Citations

Apr 12, 2005·Plant Molecular Biology·Fanchon DivolSylvie Dinant
Jan 15, 2013·Applied Biochemistry and Biotechnology·Krishnaraj ThirugnanasambanthamAbul Kalam Azad Mandal
May 3, 2003·Biochemical and Biophysical Research Communications·Patricia Company, Carmen González-Bosch
Jun 1, 2002·Current Opinion in Chemical Biology·Sergi Puig, Dennis J Thiele
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Aug 15, 2002·Plant Physiology·Teresa Balandin, Carmen Castresana
May 5, 2012·Plant Physiology·Lung-Jiun ShinKuo-Chen Yeh
Sep 27, 2003·Annual Review of Plant Biology·Catherine Curie, Jean-François Briat
Apr 11, 2012·International Journal of Molecular Sciences·Marijke JozefczakAnn Cuypers
Dec 17, 2009·Journal of Plant Physiology·Brahim SemaneJaco Vangronsveld
Jun 11, 2003·The Plant Journal : for Cell and Molecular Biology·Jason L BurkheadMarinus Pilon
Dec 22, 2005·The Plant Journal : for Cell and Molecular Biology·Nuria Andrés-ColásLola Peñarrubia
Mar 7, 2013·Journal of Integrative Plant Biology·William J LucasPradeep Kachroo
Apr 18, 2006·Current Opinion in Plant Biology·Marinus PilonHong Ye
Oct 18, 2012·Plant Signaling & Behavior·Dipesh Kumar TrivediNarendra Tuteja
Jul 22, 2006·Biochimica Et Biophysica Acta·Natasha Grotz, Mary Lou Guerinot
Jan 16, 2007·Biochemical and Biophysical Research Communications·Sergi PuigLola Peñarrubia
Nov 5, 2014·Frontiers in Plant Science·MyeongWon OhSetsuko Komatsu
May 21, 2016·Frontiers in Plant Science·Bruno PrintzKjell Sergeant
Aug 16, 2016·Frontiers in Plant Science·Manuel González-GuerreroManuel Tejada-Jiménez
Jan 17, 2004·The Journal of Biological Chemistry·Vicente SancenónLola Peñarrubia
Jan 10, 2006·Proteomics·Patrick GiavaliscoJulia Kehr
May 1, 2009·The New Phytologist·Jason L BurkheadMarinus Pilon
Jun 15, 2018·Journal of Experimental Botany·Ruthsabel O'LexyKimberly L Gallagher

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