PMID: 7337291Nov 1, 1981Paper

Evidence, nature, and implications of the constitutive resistance to Trichinella spiralis in gallinaceous birds

American Journal of Veterinary Research
O O Barriga

Abstract

White Leghorn chickens and mice were orally infected with Trichinella spiralis larvae and their digestive tracts were examined for parasites at postinfection hours (PIH) 5 and 10, and at postinfection days (PID) 1, 2, 4, 6, and 8. Evacuated feces were examined at PIH 5 and 10 and at PID 1, and blood was examined at PID 4, 6, and 8. With the exception of trichinae in the digestive tract (9 at PIH 5 and 2 at PIH 10), parasites were not recovered from chickens. All mice had abundant parasites in the digestive tract and a few parasites in the blood; however, parasites were not found in blood or feces at PID 4. In vitro incubation of infective larvae (4 hours at 37 C) in an extract of glandular stomach or in a combination of extracts from the small intestine, pancreas, and bile of chickens caused visible alterations in 42% to 64% of the larvae and caused total loss of larval infectivity for mice. Sequential incubation in both fluids caused damage in 91% to 97% of the larvae. The same experiments with mouse extracts caused damage in only 8% to 26% of the larvae and infectivity of the larvae for mice was not reduced noticeably. Digestion of infective T spiralis larvae is an important constitutive mechanism of resistance in chickens th...Continue Reading

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